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Updated: Feb 1, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Effective delayed percutaneous coronary intervention for advanced atrial ventricular block in patients with recent
Tomonori Itoh1, Toshihide Mifune1, Kentaro Komuro1
1The Department of Internal Medicine, Division of Cardiology, Memorial Heart Center, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
Insights
Late percutaneous coronary intervention (PCI) effectively restored atrio-ventricular conduction in a myocardial infarction patient with advanced atrio-ventricular block (AVB). This case demonstrates delayed PCI can be beneficial beyond the typical 12-hour window.
Area of Science:
- Cardiology
- Interventional Cardiology
- Electrophysiology
Background:
- Myocardial infarction (MI) can lead to advanced atrio-ventricular block (AVB).
- Standard treatment windows for MI complications are often within 12 hours.
- Atrio-ventricular conduction recovery is crucial for patient outcomes.
Observation:
- A 50-year-old male presented with MI 44 hours post-onset, developing advanced AVB resistant to atropine.
- Emergent coronary angiography revealed total proximal occlusion of the right coronary artery (RCA).
- Percutaneous coronary intervention (PCI) was performed on Day 5.
Findings:
- Immediate post-PCI, the patient's PR interval shortened from baseline to 0.25 s.
- Further PR interval shortening to 0.18 s was observed by Day 16.
- Successful atrio-ventricular conduction recovery was achieved through late reperfusion therapy.
Implications:
- Delayed PCI may be a viable therapeutic option for myocardial infarction patients presenting with advanced AVB beyond the conventional 12-hour window.
- This case challenges the established timeframes for intervention in MI-induced conduction abnormalities.
- Further research is warranted to explore the efficacy and safety of late reperfusion strategies in similar clinical scenarios.
Abstract:
We present a case of effective late reperfusion for atrio-ventricular conduction recovery in a patient with recent myocardial infarction complicated by advanced atrio-ventricular block (AVB). A 50-year-old Japanese man was transferred to our hospital with a recent diagnosis of myocardial infarction 44 h after onset. We performed emergent coronary angiography on Day 5 because he developed bradycardia with two to one advanced AVB resistant to atropine without chest pain or ST-T changes. Coronary angiography showed the right coronary artery (RCA) with total proximal occlusion. Emergent percutaneous coronary intervention (PCI) was performed to the RCA. Just after PCI, the PR interval was shortened to 0.25 s. Moreover, the PR interval was shortened to 0.18 s at Day 16. This report shows the new finding that delayed PCI may be effective in patients with recent myocardial infarction complicated by new AVB outside of the usual therapeutic window of 12 h.
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