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Published on: December 23, 2022
Draft Genome Sequences of the Escherichia coli Reference (ECOR) Collection
Isha R Patel1, Jayanthi Gangiredla1, Mark K Mammel1
1Division of Molecular Biology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Laurel, Maryland, USA.
This study presents the complete genomes for all 72 Escherichia coli reference (ECOR) strains. These widely used strains represent the broad phylogenetic diversity of E. coli from various sources.
Area of Science:
- Microbiology
- Genomics
- Bacterial Phylogenetics
Background:
- The Escherichia coli reference (ECOR) collection comprises 72 strains.
- These strains have been utilized for over 30 years.
- ECOR strains represent the phylogenetic diversity of E. coli.
Purpose of the Study:
- To provide the complete genome sequences for all 72 ECOR strains.
- To offer a genomic resource for understanding E. coli diversity.
Main Methods:
- Whole-genome sequencing of 72 ECOR isolates.
- Bioinformatic analysis of the generated genome data.
Main Results:
- Reported the genomes of all 72 ECOR collection isolates.
- Confirmed diverse host and geographic origins of the strains.
Conclusions:
- The genome data provides a valuable resource for E. coli research.
- Facilitates further studies on E. coli evolution and adaptation.
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