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An Allelotyping PCR for Identifying Salmonella enterica serovars Enteritidis, Hadar, Heidelberg, and Typhimurium
Published on: July 22, 2011
Draft Genome Sequence of Salmonella enterica subsp. enterica Serotype Typhimurium Sequence Type 313, Isolated from
Sohan Rodney Bangera1, Shashikiran Umakanth2, Asish K Mukhopadhyay3
1Enteric Diseases Division, Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.
Abstract:
Salmonella enterica subsp. enterica serotype Typhimurium sequence type 313 (ST313) is most commonly associated with invasive nontyphoidal Salmonella disease in Africa among patients with HIV infection and malignancy. Here, we report a draft genome sequence of S. Typhimurium ST313, isolated from an elderly immunosuppressed patient from India with non-Hodgkins lymphoma.
Insights
Salmonella Typhimurium sequence type 313 (ST313) causes invasive disease, particularly in Africa. This study reports the genome sequence of ST313 from an Indian patient with non-Hodgkin
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Salmonella enterica subsp. enterica serotype Typhimurium sequence type 313 (ST313) is a significant cause of invasive nontyphoidal Salmonella disease.
- This serotype is predominantly linked to invasive disease in African populations, often in individuals with HIV infection or malignancy.
Purpose of the Study:
- To report the draft genome sequence of S. Typhimurium ST313.
- To characterize a strain of S. Typhimurium ST313 isolated from a patient in India.
Main Methods:
- Whole-genome sequencing
- Bioinformatic analysis of the S. Typhimurium ST313 genome
Main Results:
- A draft genome sequence of S. Typhimurium ST313 was generated.
- The isolate was obtained from an elderly immunosuppressed patient in India diagnosed with non-Hodgkin's lymphoma.
Conclusions:
- This genome sequence provides valuable data for understanding the genetic makeup of S. Typhimurium ST313.
- Further research can explore the implications of this strain in diverse geographical and clinical settings.
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