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The Interaction Effect between Blood Stasis Constitution and Atherosclerotic Factors on Cognitive Impairment in

Zhizhen Liu1, Hongqing Yang2, Mozhu Zhang2

  • 1College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.

Evidence-Based Complementary and Alternative Medicine : Ecam
|December 12, 2018
PubMed

Insights

Elderly individuals with blood stasis constitution face increased risk of cognitive impairment, particularly when combined with atherosclerosis. This study highlights blood stasis as a significant factor in cognitive decline among older adults.

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Traditional Chinese Medicine

Background:

  • Blood stasis (BS) constitution is linked to atherosclerosis severity.
  • Cognitive impairment is a growing concern in the elderly population.

Purpose of the Study:

  • To investigate the interaction between blood stasis constitution and atherosclerosis in elderly cognitive impairment.
  • To identify risk factors associated with cognitive decline in older adults.

Main Methods:

  • Study included elderly individuals (≥65 years) from Fuzhou city in 2015.
  • Compared TCM constitution and atherosclerotic factors between normal and cognitive impairment groups.
  • Analyzed interactions using Minimental State Examination (MMSE) scores.

Main Results:

  • Cognitive impairment prevalence was 13.0% in the study cohort.
  • Blood stasis, RBC, HB, ABI, and BaPWV differed significantly between groups.
  • Blood stasis constitution, RBC, HB, and ABI were correlated with cognitive impairment.

Conclusions:

  • Blood stasis constitution increases risk for arterial stenosis and sclerosis.
  • These vascular changes contribute to cognitive impairment susceptibility in the elderly.
  • Interactions of blood stasis with HB, ABI, and BaPWV impact cognitive function (MMSE scores).
Abstract

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