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Updated: Feb 1, 2026

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice
Published on: September 17, 2015
A case with a huge left ventricular thrombus growing over the posterior papillary muscle and chordae tendinae
Zeki Dogan1, Ahmet Karabulut1, Bulent Uzunlar1
1Department of Cardiology, Istanbul Medicine Hospital, Istanbul, Turkey.
Abstract:
We present a case with a giant left ventricular thrombus grown over papillary muscle and chordae tendinae. The patient had declined both surgical and fibrinolytic therapy. After long-term anticoagulation therapy, regression was observed without embolic complication. Anticoagulation with warfarin may be preferred in such cases presenting with huge left ventricular thrombus encircling papillary muscle and chordae tendinae. <Learning Objective: There are no clear-cut guidelines about the treatment strategies for huge ventricular thrombus. Herein, we present a case of giant left ventricular thrombus grown over papillary muscle and chordae tendinae. We showed that long-term anticoagulation may be effective for patients with huge ventricular thrombus grown over papillary muscle and chordae tendinae.>.
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