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DICAM Attenuates Experimental Colitis via Stabilizing Junctional Complex in Mucosal Barrier

Seung-Woo Han1, Jeong Min Kim2, Yunmee Lho3

  • 1Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.

Inflammatory Bowel Diseases
|December 12, 2018
PubMed
Summary

Dual immunoglobulin domain-containing adhesion molecule (DICAM) expression increases during colitis and protects the intestinal barrier. Loss of DICAM worsens colitis, while its overexpression maintains barrier integrity, highlighting its protective role.

Keywords:
DICAMadhesion moleculecolitismucosal barrier

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