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WIlsON: Web-based Interactive Omics VisualizatioN.

Hendrik Schultheis1, Carsten Kuenne1, Jens Preussner1

  • 1Max Planck Institute for Heart and Lung Research, Bioinformatics Core Unit (BCU), 61231 Bad Nauheim, Germany.

Bioinformatics (Oxford, England)
|December 12, 2018
PubMed
Summary
This summary is machine-generated.

WIlsON is a new interactive workbench for analyzing and visualizing multi-omics data. This tool empowers scientists to explore high throughput screening results dynamically, generating publication-ready plots without computational expertise.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Visualization

Background:

  • High throughput (HT) omics screens generate large datasets typically analyzed by automated pipelines.
  • Static visualizations and spreadsheets limit exploratory and hypothesis-driven data analysis in biological systems.
  • There is a need for customized and dynamic visualization tools for omics data.

Purpose of the Study:

  • To introduce WIlsON, an interactive workbench for multi-omics data analysis and visualization.
  • To enable non-computational scientists to access and analyze pre-calculated HT screen results.
  • To support exploratory data analysis and hypothesis generation in omics research.

Main Methods:

  • WIlsON is implemented in R, utilizing the modular Shiny and Plotly frameworks for extensibility.
  • It supports all omics screen types through an open file format.
  • Results are served via a web-based dashboard for user interaction.

Main Results:

  • WIlsON provides an interactive workbench for multi-omics data analysis.
  • It allows end-users to perform analyses and generate publication-ready plots.
  • The tool empowers screening platforms to offer dynamic data exploration to scientists.

Conclusions:

  • WIlsON facilitates dynamic and exploratory analysis of high throughput omics screening data.
  • It bridges the gap between raw data and scientific insight for non-computational users.
  • The workbench enhances the accessibility and utility of omics screening results.