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Updated: Feb 1, 2026

Isolation and Enrichment of Liver Progenitor Subsets Identified by a Novel Surface Marker Combination
Published on: February 18, 2017
Analysis for the Heterogeneity of Liver Progenitor Cells
1Department of Developmental Biology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. kamimoto@wustl.edu.
Abstract:
Recent technological advances have revealed the heterogeneity of cells and tissues. Existence of heterogeneity in hepatic progenitor cells is becoming apparent by various experimental approaches, and here we describe a series of techniques to investigate the proliferative heterogeneity of these cells. We have developed a new technique by combining genetic lineage tracking and three-dimensional imaging methods. The data obtained can be used in statistical analysis to quantitatively investigate the mechanisms underlying the heterogeneity of hepatic progenitor cells.
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