Related Experiment Video
Updated: Feb 1, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
Comparison of demographic data, disease severity and response to treatment, between dogs with atopic dermatitis and
Larissa S Botoni1, Sheila M F Torres2, Sandra N Koch2
1Department of Veterinary Clinical Sciences and Surgery, Universidade Federal de Minas Gerais, 6627 Antônio Carlos Ave, Belo Horizonte, 31270-901, Brazil.
Background:
Limited information is available describing the features of canine atopic-like dermatitis (ALD) compared with atopic dermatitis (AD).
Objectives:
To compare demographic data, disease severity and response to therapy between ALD and AD dogs.
Animals:
Two hundred and fifty-three atopic dogs with intradermal and serum allergen-specific IgE test results were selected retrospectively.
Methods And Materials:
Dogs were enrolled into the ALD group if both IgE tests were negative and into the AD group if at least one test was positive. Demographic data, pruritus level and number of body sites affected before and during therapy, in addition to maintenance therapy protocols, were compared between groups.
Results:
There were 216 (85.38%) dogs in the AD group and 37 (14.62%) in the ALD group. The soft-coated wheaten terrier, American Staffordshire terrier, English bulldog and Labrador retriever were over-represented in the AD group. No significant differences between the groups were noted regarding the other demographic variables evaluated. There were no differences in the mean pruritus scores and number of affected body sites at the first visit or during treatment. Furthermore, no significant differences between the groups were noted for the maintenance treatment scores and reduction of pruritus level and number of body sites affected during treatment.
Conclusions And Clinical Significance:
The soft-coated wheaten terrier, American Staffordshire terrier, English bulldog and Labrador retriever were over-represented in the AD group. No significant differences in the other demographic data and clinical features were noted between dogs with ALD and AD in the present study.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Alzheimer's Disease: Treatment
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...

