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Same day versus next day antroduodenal manometry results in children with upper gastrointestinal symptoms: A

Ricardo A Arbizu1, Samuel Nurko1, Nicole Heinz1

  • 1Center for Motility and Gastrointestinal Functional Disorders, Division of Gastroenterology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Neurogastroenterology and Motility
|December 12, 2018
PubMed

Insights

Antroduodenal manometry (ADM) results differ significantly when performed the day after catheter placement compared to the day of. Motility index and phase III of the migrating motor complex were higher on day 2, altering study interpretations.

Area of Science:

  • Gastroenterology
  • Physiology

Background:

  • Antroduodenal manometry (ADM) assesses gastrointestinal motility.
  • Standard ADM protocols involve catheter placement and subsequent testing.

Purpose of the Study:

  • To evaluate changes in ADM parameters and interpretation between the day of catheter placement and the following day.
  • To determine the impact of catheter placement timing on ADM results.

Main Methods:

  • Twenty patients underwent endoscopic catheter placement for ADM.
  • ADM parameters were recorded on day 1 (placement day) and day 2.
  • Parameters included motility index (MI), phase III of the migrating motor complex (MMC), and responses to erythromycin (EES) and octreotide (OCT) challenges.

Main Results:

  • Antrum and small bowel MI were significantly higher on day 2 compared to day 1 (P < 0.05).
  • The presence of phase III of the MMC was significantly higher on day 2 (65% vs 15%; P = 0.006).
  • Study interpretations changed in 20% of patients between day 1 and day 2.

Conclusions:

  • ADM parameters are influenced by the day of catheter placement.
  • Higher motility and MMC phase III presence on day 2 suggest improved readings post-placement.
  • A significant proportion of ADM studies may require re-interpretation due to day-of-placement effects.
Abstract

Keywords:
anesthesiamanometrymigrating motor complexpediatrics

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