Related Experiment Video
Updated: Oct 1, 2026

07:42
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
The molecular analysis of chromosomal translocations as a diagnostic, epidemiological and potentially prognostic tool
I Magrath1, F Barriga, M McManaway
1Pediatric Branch, National Cancer Institute, Bethesda, Maryland 20892.
Journal of Virological Methods
|September 1, 1988
Abstract:
Neoplasms have been shown to be associated with specific non-random chromosomal abnormalities. The present paper summarizes molecular consequences of chromosomal translocations in lymphoid malignancies, especially in Burkitt's lymphoma. Among such consequences are derangements of the regulation of oncogene transcription. Besides their possible importance for lymphoma pathogenesis, chromosomal translocations are associated in some lymphoid neoplasms with a worse prognosis.

