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Human herpesvirus-6 (HHV-6, HBLV) in sarcoidosis and lymphoproliferative disorders
P Biberfeld1, A L Petrén, A Eklund
1Department of Pathology, Karolinska Institute, Stockholm, Sweden.
Journal of Virological Methods
|September 1, 1988
Abstract:
Serologic studies were done to estimate the antibody prevalence against human herpesvirus 6 (HHV-6) in patients with malignant lymphomas, Sjögren's syndrome and sarcoidosis. Serologic studies showed IgG antibody titers against HHV-6 in up to 41% of patients with sarcoidosis, 50-70% with malignant lymphomas and in 36% with Sjögren's syndrome. In situ hybridization on lymph node biopsies was positive for HHV-6 genome in 1 out of 5 sarcoidosis lymph nodes.