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Published on: July 11, 2019
Predictors of venous stenosis or occlusion following first transvenous cardiac device implantation: Prospective
Andrzej Cacko1, Eliza Kozyra-Pydyś2, Monika Gawałko2
11 Department of Medical Informatics and Telemedicine, Medical University of Warsaw, Warsaw, Poland.
Insights
Venous stenosis or occlusion after cardiac device implantation is linked to longer procedures and complications. Interestingly, diabetes or prediabetes appears to reduce this risk.
Area of Science:
- Cardiology
- Vascular Medicine
- Medical Devices
Background:
- Venous stenosis or occlusion is a known complication of intracardiac devices.
- Previous studies focused on device upgrades or lead extractions, not initial implantations.
Purpose of the Study:
- To assess the prevalence of venous stenosis or occlusion after first transvenous cardiac device implantation.
- To identify predictors of venous stenosis or occlusion in this patient population.
Main Methods:
- Prospective observational study of 71 consecutive patients undergoing first transvenous cardiac device implantation.
- Follow-up duration of 6 months post-operation.
Main Results:
- The incidence of venous stenosis or occlusion within 6 months was 21.1%.
- Predictors identified include prolonged procedure time (OR: 4.54) and perioperative complications (OR: 7.04).
- Diabetes or prediabetes was associated with a reduced risk (OR: 0.17).
Conclusions:
- Prolonged implantation time and perioperative complications increase the risk of venous stenosis or occlusion.
- Diabetes and prediabetes are associated with a significantly reduced risk of venous stenosis or occlusion following initial cardiac device implantation.
Introduction:
Venous stenosis or occlusion related to an intracardiac device is a well-known complication of that procedure. There are numerous studies tried to determine predictors of venous stenosis or occlusion; however, most of them investigate the venous system prior to device upgrade, generator replacement, or transvenous lead extraction. Therefore, we aimed to assess the prevalence and determine the predictors of venous stenosis or occlusion following first transevnous cardiac device implantation.
Methods:
Observational, prospective study included 71 consecutive patients admitted for first transvenous cardiac device implantation. All patients were followed up for 6 months after operation.
Results:
Implanted device systems comprised cardioverter defibrillator (n = 26), single-chamber or dual-chamber pacemakers (n = 34), and biventricular pacemakers (n = 11); 88.5% of implantable cardioverter defibrillator leads were single-coils and 11.5% were dual-coils. The incidence of venous stenosis or occlusion within 6-month follow-up was 21.1%. Multivariate logistic regression showed that only diabetes or prediabetes (p = 0.033, odds ratio: 0.17, 95% confidence interval: 0.04-0.87), prolonged procedure time (p = 0.046, odds ratio: 4.54, 95% confidence interval: 1.01-20.12), and perioperative complications (p = 0.021, odds ratio: 7.04, 95% confidence interval: 1.35-36.85) were predictors of venous stenosis or occlusion.
Conclusion:
Prolonged implantation time (>60 min) and perioperative complications are associated with an increased risk of venous stenosis or occlusion, whereas diabetes and prediabetes significantly reduce the risk of venous stenosis or occlusion.
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