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Mycoplasma pneumoniae infection and asthma in children

Surinder Kumar1, Ruma Dev Roy2, G R Sethi3

  • 11 Director Professor, Department of Microbiology, Maulana Azad Medical College, New Delhi, India.

Tropical Doctor
|December 13, 2018
PubMed

Insights

Mycoplasma pneumoniae infections are frequently linked to asthma exacerbations in children. This study confirms the association between lower respiratory tract infections and worsening asthma symptoms.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Clinical Immunology

Background:

  • A suspected clinical link exists between asthma exacerbations and Mycoplasma pneumoniae infections.
  • Mycoplasma pneumoniae is a common respiratory pathogen in children.

Purpose of the Study:

  • To investigate the association between Mycoplasma pneumoniae infection and asthma exacerbations in children.
  • To confirm the role of M. pneumoniae in pediatric asthma flares.

Main Methods:

  • Studied 80 children aged 5-15 years, divided into asthma (n=50) and non-asthma (n=30) groups.
  • Detected M. pneumoniae using serology and polymerase chain reaction (PCR) on nasopharyngeal aspirates.

Main Results:

  • Confirmed frequent association between lower respiratory tract infections caused by M. pneumoniae and asthma exacerbations.
  • M. pneumoniae detection was higher in children experiencing asthma flares.

Conclusions:

  • Mycoplasma pneumoniae infections are significantly associated with exacerbations of asthma in pediatric patients.
  • Clinical suspicion of M. pneumoniae should be considered in children with acute asthma symptoms.
Keywords:
Asthmabacterial infectiondiagnosisdiseaserespiratory tract infections

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