A quarter of a century of SERF: The progress of an NMR pulse sequence and its application
Related Experiment Video
Updated: Feb 1, 2026

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
1Institute of Analytical Chemistry, University Leipzig, Johannisallee 29, D-04103 Leipzig, Germany.
Abstract:
SERF, an NMR pulse sequence for selectively measuring a spin coupling constant without interference from other couplings, was published by the current author almost 25 years ago in 1995. Since then, about 35 modifications and extensions of the original have been published by other groups and applied to many chemical problems. This review discusses these modifications and provides pertinent examples. A comparative and critical evaluation of these developments is given in tabular form. The last part focuses on the chemical results.
More Related Videos
07:54Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy
Published on: December 15, 2011
09:24Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
Published on: August 22, 2017
Related Concept Videos
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
Applications Of NMR In Biology
Pulse
The pulse serves as a clinical...
Pulse
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
Regulation of Pulse