Related Experiment Video
Updated: Feb 1, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Biomarker-based corticosteroid adjustment in severe asthma: a modified Delphi consensus
Nicola E Gallagher1, Catherine E Hanratty1, Marc Humbert2,3
1Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK.
UK physicians support biomarker-based asthma treatment adjustments. However, European doctors require additional evidence before adopting these advanced steroid management strategies.
Area of Science:
- Pulmonology
- Clinical Medicine
- Respiratory Medicine
Background:
- Asthma management often involves adjusting corticosteroid therapy.
- Biomarker-guided treatment offers a potential approach for personalized medicine.
Purpose of the Study:
- To assess the perspectives of UK and European physicians on biomarker-based steroid adjustment in asthma care.
- To identify barriers and facilitators for implementing advanced treatment strategies.
Main Methods:
- Survey distributed to UK and European asthma specialists.
- Data collection on attitudes towards and perceived needs for biomarker-guided therapy.
Main Results:
- UK physicians show strong support for biomarker-based steroid adjustment.
- European physicians express a need for more robust clinical evidence and guidelines.
Conclusions:
- Biomarker-guided asthma management is promising but requires further validation in Europe.
- Physician acceptance is crucial for the successful integration of new therapeutic approaches.
Related Concept Videos
Asthma-I: Introduction
The Anchoring-and-Adjustment Heuristic
Adjusting a Traverse
COPD: Management Using Bronchodilators and Corticosteroids
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

