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Updated: Feb 1, 2026

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart
Published on: April 27, 2016
A Minimally Invasive Approach for Placing Sew-On Epicardial Leads in the Child
Joseph R Nellis, Zachary W Fitch, Ashley Y Choi
1Pediatric & Congenital Heart Center, Duke Children's Hospital, Durham, NC USA.
Abstract:
Traditionally, pacing leads are placed transvenously, although smaller pediatric patients who require permanent pacemakers may benefit from delaying tranvenous lead placement until they are larger. Alternative, minimally invasive atrioventricular pacing options have not previously existed for this patient population, leaving many of these children with large sternotomies or thoracotomies. Using three port sites and an adjustable shaft dual-needle suturing device, we placed a steroid-eluting, sew-on epicardial lead on the right atrium of a 9-year-old patient. This is one of the earliest reported cases of a minimally invasive technique for sew-on epicardial lead placement on the atrium of a child. Although based on a single case, we believe that this approach is safe, reliable, and reproducible and that it can be used to place leads on any aspect of the heart. Adoption of this technique will allow for earlier atrioventricular pacing, which may decrease the incidence of pacemaker syndrome, and thus improve overall outcomes in this patient population.
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