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[Fulminating ischemic hepatitis induced by severe cardiac dysfunction: case report].

Josué J Aliaga Ramos1, Jorge Espinoza-Ríos1, Vanessa Valenzuela Granados2

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Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|December 13, 2018
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Summary
This summary is machine-generated.

Ischemic hepatitis, a critical care condition with high mortality, involves severe liver hypoperfusion causing rapid transaminase increases. Prompt treatment of the underlying cause, such as cardiac dysfunction, can lead to transient recovery.

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Area of Science:

  • Hepatology
  • Critical Care Medicine
  • Cardiology

Background:

  • Ischemic hepatitis is an uncommon critical care unit entity (0.16-0.5% prevalence) with a high mortality rate (approx. 60%).
  • It is defined by marked transaminase elevation (>20x normal) due to severe hepatic hypoperfusion.
  • Multiple etiologies can cause hepatic hypoperfusion, and timely treatment of the trigger can lead to transient resolution.

Observation:

  • This report details a case of ischemic hepatitis in an elderly adult.
  • The patient presented with a clinical, epidemiological, and biochemical profile consistent with this diagnosis.
  • The underlying cause identified was severe cardiac dysfunction.

Findings:

  • The patient's presentation strongly indicated ischemic hepatitis.
  • Severe cardiac dysfunction was identified as the primary etiology.
  • The biochemical markers, specifically transaminases, showed a significant increase consistent with liver injury.

Implications:

  • This case highlights the importance of recognizing ischemic hepatitis in critically ill patients.
  • Identifying and treating the underlying cause, such as cardiac dysfunction, is crucial for potential recovery.
  • Early diagnosis and management can improve outcomes for patients with ischemic hepatitis.