Simultaneous operative repair of pectus excavatum and concurrent congenital heart defects

Guangxian Yang1,2, Xicheng Deng2, Yifeng Yang1

  • 1Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.

Insights

This study shows that simultaneous surgical repair of pectus excavatum (PE) and congenital heart defects (CHD) in children is safe and effective. The combined approach leads to satisfactory outcomes and high patient satisfaction.

Area of Science:

  • Pediatric Surgery
  • Cardiology
  • Thoracic Surgery

Background:

  • Pectus excavatum (PE) and congenital heart defects (CHD) can coexist in children.
  • Managing these concurrent conditions requires careful surgical planning.

Purpose of the Study:

  • To describe an effective surgical strategy for simultaneous repair of PE and CHD in pediatric patients.
  • To evaluate the safety and efficacy of combined surgical interventions.

Main Methods:

  • Retrospective review of 16 pediatric patients undergoing simultaneous PE and CHD repair.
  • PE repair involved open sternal elevation, Nuss repair, or custom device.
  • CHD repair utilized open heart surgery, transcatheter closure, or percutaneous intervention.

Main Results:

  • All 16 patients achieved satisfactory repair of both PE and CHD.
  • No serious complications were reported postoperatively.
  • High satisfaction rates were reported by patients and parents regarding chest appearance.

Conclusions:

  • Simultaneous elective repair of PE and concurrent CHD is a safe and effective strategy.
  • This combined approach avoids risks associated with staged operations.
  • Satisfactory outcomes and patient satisfaction are achievable with tailored surgical plans.
Abstract

Related Concept Videos

Mismatch Repair01:36

Mismatch Repair

Overview
43.7K
Overview of DNA Repair02:25

Overview of DNA Repair

In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
Chemically...
33.7K
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.3K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

Overview
40.8K
Lumber Defects01:23

Lumber Defects

Lumber defects, which can affect both the appearance and structural integrity of wood, include a variety of growth and manufacturing flaws. Growth defects such as knots and knotholes occur where branches were once attached to the tree trunk, with knotholes forming when these knots fall out. Other natural defects include decay and insect damage, which compromise the wood's strength and durability.
Shakes are minor fractures that run along or across the wood's annual rings, while wane is...
520
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.0K