Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

Factors Influencing Drug Absorption: Pharmaceutical Parameters

525
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
525
Factors Influencing Drug Absorption: Anatomical Parameters01:23

Factors Influencing Drug Absorption: Anatomical Parameters

632
Drug absorption involves the movement of drugs from the point of administration into the systemic circulation. Initially, Gastrointestinal (GI) motility propels the drug through the digestive tract and into the stomach. However, the stomach's high acidity and limited surface area restrict its role in drug absorption for most drugs. The drug then moves from the stomach to the small intestine via gastric emptying, which can be slowed by various factors, including interactions with other...
632
Factors Influencing Drug Absorption: Physicochemical Parameters01:22

Factors Influencing Drug Absorption: Physicochemical Parameters

851
The physicochemical characteristics of drugs play a crucial role in formulating stable and bioavailable drug products. The solubility of a drug, governed by the varying pH along the GI tract and its dissociation constant (pKa), is pivotal in determining its ionization state and absorption rate. Notably, weak acids and bases remain unionized and are absorbed more rapidly.
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
851
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

812
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
812
Wave Parameters01:10

Wave Parameters

9.3K
The simplest mechanical waves are associated with simple harmonic motion and repeat themselves for several cycles. These simple harmonic waves can be modeled using a combination of sine and cosine functions. Consider a simplified surface water wave that moves across the water's surface. Unlike complex ocean waves, in surface water waves, water moves vertically, oscillating up and down, whereas the disturbance of the wave moves horizontally through the medium. If a seagull is floating on the...
9.3K
The Influence of Affect on Cognition01:29

The Influence of Affect on Cognition

285
Positive affect significantly influences cognitive processes, including evaluation, memory, creativity, and social judgments. Compared to negative affect, positive emotional states promote more favorable interpretations of stimuli, cognitive flexibility, and heuristic processing. These effects highlight emotions' powerful role in shaping how individuals perceive, remember, and interact with the world.Influence on Evaluation and AttributionWhen individuals experience positive affect, they are...
285

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of adherence to fixed-dose combination therapy in the treatment of cardiovascular risk factors in primary care.

Semergen·2024
Same author

[Therapeutic adherence of patients with cardiovascular risk in primary care. REAAP project].

Semergen·2023
Same author

[Improved profitability and indications for blood culture extraction in emergency departments: another step forward].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022
Same author

[Importance of blood cultures results: and special attention for applicants from the Emergency Departament].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2020
Same author

[COVID-19. History repeats itself and we keep stumbling on the same stone].

Semergen·2020
Same author

[Skills perceived by general practitioners for providing care to immigrant patients].

Semergen·2020
Same journal

[Adult ADHD: Underdiagnosis, healthcare barriers, and the role of primary care].

Semergen·2026
Same journal

Mepifilina in Spain: Accessible evidence, guideline positioning, utilization and proportionate reassessment.

Semergen·2026
Same journal

Trends and disparities in influenza and pneumonia associated sepsis mortality among older adults in the United States, 1999-2022: A retrospective population-based study.

Semergen·2026
Same journal

[High-impact ultrashort simulation-based pulmonary ultrasound training for Family Medicine residents: A prospective educational innovation study].

Semergen·2026
Same journal

[Biopsychosocial intervention for chronic non-cancer pain in Primary Care].

Semergen·2026
Same journal

[Underestimation of Glomerular Filtration Rate Obtained with Serum Creatinine-Based Formulas Compared to Those Using Serum Cystatin in Patients with Increased Muscle Mass].

Semergen·2026
See all related articles

Related Experiment Video

Updated: Feb 1, 2026

Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice
16:09

Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice

Published on: October 4, 2014

17.1K

[Baseline spirometry parameters that can influence the bronchodilation test].

I Rodríguez Clérigo1, I Nieto Rojas1, R Mota Santana1

  • 1Medicina de Familia, Centro de Salud Sillería, Toledo, España.

Semergen
|December 14, 2018
PubMed
Summary
This summary is machine-generated.

Baseline spirometry measurements significantly impact bronchodilation test (BDT) positivity. Forced expiratory volume and vital capacity influence BDT results, suggesting these factors should be considered for future diagnostic criteria.

Keywords:
Atención primariaBronchodilation testEspirometríaParámetros respiratoriosPrimary CarePrueba de broncodilataciónRespiratory parametersSpirometry

More Related Videos

Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

28.6K
Fabric Moisture Uniform Control to Study the Influence of Air Impingement Parameters on Fabric Drying Characteristics
06:28

Fabric Moisture Uniform Control to Study the Influence of Air Impingement Parameters on Fabric Drying Characteristics

Published on: August 19, 2019

5.6K

Related Experiment Videos

Last Updated: Feb 1, 2026

Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice
16:09

Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice

Published on: October 4, 2014

17.1K
Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

28.6K
Fabric Moisture Uniform Control to Study the Influence of Air Impingement Parameters on Fabric Drying Characteristics
06:28

Fabric Moisture Uniform Control to Study the Influence of Air Impingement Parameters on Fabric Drying Characteristics

Published on: August 19, 2019

5.6K

Area of Science:

  • Pulmonary Medicine
  • Respiratory Diagnostics
  • Clinical Physiology

Background:

  • Bronchodilation testing (BDT) is crucial for diagnosing reversible airway obstruction.
  • Standardized interpretation of BDT results is essential for accurate diagnosis and management.
  • Baseline spirometry parameters may affect BDT outcomes, necessitating further investigation.

Purpose of the Study:

  • To investigate the influence of baseline forced spirometry parameters on bronchodilation test (BDT) positivity.
  • To assess the potential impact of these baseline parameters on future BDT positivity criteria.

Main Methods:

  • A descriptive, cross-sectional study was conducted in a primary care setting.
  • 295 patients undergoing spirometry with BDT between June 2015 and February 2017 were included.
  • Data on baseline spirometry (FEV1, FVC) and BDT results were analyzed.

Main Results:

  • A positive BDT was observed in 8.8% of patients.
  • Patients with percentage-positive BDT showed lower baseline FEV1 and FVC.
  • Patients with volume-positive BDT had lower baseline FEV1 and higher FVC.

Conclusions:

  • Baseline forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC) significantly influence BDT positivity.
  • These baseline spirometry findings should be considered when establishing BDT positivity criteria.