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Bronchopulmonary dysplasia: Pathogenesis and treatment
Asfia Banu Pasha1, Xiao-Qing Chen1, Guo-Ping Zhou1
1Department of Pediatrics, The First Affiliated Hospital, School of International Education, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Experimental and Therapeutic Medicine
|December 14, 2018
Summary
Bronchopulmonary dysplasia (BPD) affects premature infants, causing chronic lung disease. Emerging therapies like recombinant human superoxide dismutase show promise in reducing respiratory injury and long-term effects.
Area of Science:
- Neonatology
- Pediatric Pulmonology
- Critical Care Medicine
Background:
- Bronchopulmonary dysplasia (BPD) is a significant cause of chronic lung disease in infancy, primarily affecting premature infants.
- Premature infants treated for conditions like respiratory distress syndrome face an elevated risk of developing BPD.
- Despite clinical advancements, the incidence of BPD remains a persistent challenge.
Purpose of the Study:
- To review the pathogenesis of Bronchopulmonary dysplasia (BPD).
- To outline current treatment and nursing management strategies for BPD.
- To discuss emerging preventive therapies for BPD.
Main Methods:
- Literature review focusing on BPD pathogenesis, current treatments, nursing roles, and preventive strategies.
- Analysis of existing clinical data and research on BPD management.
- Inclusion of studies on novel therapeutic agents such as recombinant human superoxide dismutase.
Main Results:
- The review details the complex pathogenesis of BPD.
- Current management strategies and the crucial role of nursing care are described.
- Emerging preventive therapies, including recombinant human superoxide dismutase, demonstrate potential in mitigating respiratory injury.
Conclusions:
- Bronchopulmonary dysplasia (BPD) remains a critical issue in neonatal care.
- A comprehensive approach involving current treatments, nursing support, and novel preventive therapies is essential.
- Recombinant human superoxide dismutase presents a promising avenue for reducing BPD-related respiratory injury and long-term complications.
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