Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

40.8K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
40.8K
Polymers02:34

Polymers

23.3K
23.3K
Lewis Acids and Bases02:33

Lewis Acids and Bases

48.4K
In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
48.4K
Crossing Over01:34

Crossing Over

171.9K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
171.9K
Monohybrid Crosses01:20

Monohybrid Crosses

239.5K
Overview
239.5K
Cross-Sectional Research01:50

Cross-Sectional Research

12.5K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring Important Features in Continuous Spectral Datasets Using Supervised Learning.

Analytical chemistry·2026
Same author

CO<sub>2</sub>-Assisted Hydrolysis of NaBH<sub>4</sub>: A Multi-Function Platform for Enhanced Hydrogen Release, Regeneration of NaBH<sub>4</sub>, and CO<sub>2</sub>-to-CH<sub>4</sub> Conversion.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Single-Step Grafting of a Thermoresponsive RAFT Polymer from Nanocellulose by Radical Decarboxylation.

ACS polymers Au·2026
Same author

Isolation and synthesis of bisabosquals, fungal triprenyl phenol meroterpenoids with a densely functionalised bisabolane core.

Natural product reports·2026
Same author

Enantioselective Total Synthesis of (-)-Bisabosqual F via N-Heterocyclic Carbene Catalyzed (4+2) Annulation.

Angewandte Chemie (International ed. in English)·2025
Same author

Phosphine-Mediated (3 + 2) Cycloaddition of Electron-Poor Terminal Alkynes: A Concise Route to Premethylenomycin C Lactone.

The Journal of organic chemistry·2025

Related Experiment Video

Updated: Feb 1, 2026

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes
07:26

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes

Published on: February 22, 2012

19.8K

RAFT polymer cross-coupling with boronic acids.

Hartwig Golf1, Riley O'Shea1, Carl Braybrook2

  • 1School of Chemistry , Monash University , Clayton , Melbourne , VIC 3800 , Australia . Email: david.lupton@monash.edu ;

Chemical Science
|December 14, 2018
PubMed
Summary
This summary is machine-generated.

Modifying thiocarbonylthio end-groups of RAFT polymers is crucial for creating inert or functional materials. A new copper-promoted cross-coupling reaction with aryl boronic acids achieves high conversion for versatile polymer modification.

More Related Videos

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

3.5K
Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
09:46

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores

Published on: August 19, 2013

16.0K

Related Experiment Videos

Last Updated: Feb 1, 2026

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes
07:26

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes

Published on: February 22, 2012

19.8K
Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

3.5K
Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
09:46

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores

Published on: August 19, 2013

16.0K

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Reversible Addition-Fragmentation chain Transfer (RAFT) polymerization is a powerful technique for controlled polymer synthesis.
  • Modification of polymer end-groups is essential for tailoring material properties and enabling advanced applications.
  • Thiocarbonylthio end-groups from RAFT polymerization offer a reactive handle for post-polymerization modification.

Purpose of the Study:

  • To develop a novel method for efficient modification of RAFT polymer thiocarbonylthio end-groups.
  • To introduce a versatile cross-coupling reaction compatible with various functional molecules.
  • To enable the synthesis of inert or highly functionalized polymers for diverse applications.

Main Methods:

  • Utilized a copper-promoted cross-coupling reaction.
  • Employed aryl boronic acids as coupling partners for RAFT polymer end-groups.
  • Investigated reaction conditions to optimize conversion and compatibility.

Main Results:

  • Achieved high conversion rates for the modification of RAFT polymer end-groups.
  • Demonstrated compatibility with a wide range of functional molecules.
  • Successfully synthesized modified polymers with tailored properties.

Conclusions:

  • The reported copper-promoted cross-coupling reaction provides an efficient and versatile route for modifying RAFT polymer end-groups.
  • This method facilitates the creation of advanced polymeric materials with tunable functionalities.
  • The approach is valuable for applications requiring inert or specifically functionalized polymers.