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Updated: Feb 1, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Effective Ibuprofen Desensitization in a Patient with Myopericarditis
Gabriele Cortellini1, Domenico Lippolis2, Silvia Amati3
1Internal Medicine, Allergy Unit, Rimini Hospital, Azienda Sanitaria Romagna, Rimini, Italy, gcortellini@libero.it.
Abstract:
To date, aspirin desensitization is employed with patients with nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbated respiratory diseases (NERD) or with aspirin or NSAIDs hypersensitive patients needing a stent procedure for coronary artery disease. On the other hand, few data exist regarding aspirin desensitization in other cardiological features and particularly we haven't data on different NSAIDs desensitization. Only for NERD patients we have data on ketorolac use. We report an efficacious desensitization procedure for ibuprofen in urticaria/angioedema patient with pericarditis and myocarditis associated.
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