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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Current Activities of the Coalition of Cancer Cooperative Groups
Monica M Bertagnolli1, Susan M Blaney2, Charles D Blanke3
1Department of Surgery, Division of Surgical Oncology, Brigham and Women's Hospital, Boston, MA.
Abstract:
The Coalition of Cancer Cooperative Groups is an organization representing the interests of patients and researchers who conduct research through the National Cancer Institute-supported National Clinical Trials Network (NCTN). The NCTN provides a crucial mechanism for executing practice-changing cancer clinical research to achieve both cancer control and development of new therapeutic agents or modality approaches. Public funding, largely through the National Cancer Institute, ensures that the work of the NCTN achieves important research that would not otherwise be accomplished in the private sector. In fall 2017, the Coalition of Cancer Cooperative Groups convened a Scientific Leadership Council to review the current state of the network with regard to research capabilities and to develop a list of research questions to be prioritized by the network. This report presents the results of this meeting, detailing a roadmap for future work by the NCTN.
Insights
The National Clinical Trials Network (NCTN) advances cancer research through public funding. A 2017 meeting outlined a strategic roadmap to prioritize future NCTN research initiatives for improved cancer control and therapies.
Area of Science:
- Oncology
- Clinical Trials Research
- Cancer Therapeutics
Background:
- The National Clinical Trials Network (NCTN) is vital for practice-changing cancer research.
- Public funding, primarily from the National Cancer Institute, supports critical research not feasible in the private sector.
Purpose of the Study:
- To review the current research capabilities of the NCTN.
- To identify and prioritize future research questions for the NCTN.
Main Methods:
- Convening of a Scientific Leadership Council by the Coalition of Cancer Cooperative Groups in Fall 2017.
- Review of the NCTN's research landscape and capabilities.
- Development of a prioritized list of research questions.
Main Results:
- Assessment of the NCTN's existing research strengths and limitations.
- Identification of key areas for future research focus.
- A defined roadmap for the NCTN's future endeavors.
Conclusions:
- The NCTN is a critical infrastructure for advancing cancer care.
- Strategic prioritization of research questions will guide future NCTN work.
- The outlined roadmap will direct future NCTN research efforts for enhanced cancer control and therapeutic development.
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