Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Physiology of Enteric Nervous System and Gut Health01:05

Physiology of Enteric Nervous System and Gut Health

978
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
978
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

1.7K
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
1.7K
Routes of Drug Administration: Enteral01:18

Routes of Drug Administration: Enteral

6.4K
Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
6.4K
Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

1.8K
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
1.8K
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

1.5K
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
1.5K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

991
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
991

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rational engineering of facultative anaerobiosis enables commensal survival in the oxygenated gut.

bioRxiv : the preprint server for biology·2026
Same author

Periplasmic detoxification of urate hydroperoxide underpins <i>E. coli</i> survival in the inflamed gut.

bioRxiv : the preprint server for biology·2026
Same author

Cholera-toxin-induced disease generates epithelial-cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine.

Cell reports·2026
Same author

<i>Salmonella</i> lipopolysaccharide stimulates uptake of long-chain fatty acids in the small intestine.

bioRxiv : the preprint server for biology·2026
Same author

Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance.

Cell host & microbe·2026
Same author

An anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gut.

Cell·2026

Related Experiment Video

Updated: Feb 1, 2026

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.7K

Using Enteric Pathogens to Probe the Gut Microbiota.

Luisella Spiga1, Sebastian E Winter1

  • 1Department of Microbiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, USA.

Trends in Microbiology
|December 15, 2018
PubMed
Summary
This summary is machine-generated.

Enteric pathogens reveal gut microbiota functions during inflammation. Studying host-microbe interactions, especially metabolic pathways, can lead to new microbiota-targeted therapies.

Keywords:
enteric pathogensgut microbiotamicrobial metabolism

More Related Videos

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.9K
Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization
08:30

Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization

Published on: June 1, 2018

10.0K

Related Experiment Videos

Last Updated: Feb 1, 2026

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.7K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.9K
Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization
08:30

Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization

Published on: June 1, 2018

10.0K

Area of Science:

  • Microbiology
  • Immunology
  • Gastroenterology

Background:

  • Enteric pathogens can alter host-microbe interactions during gut inflammation.
  • Understanding these interactions is crucial for managing inflammatory conditions.
  • Commensal microbial communities play a significant role in gut health.

Purpose of the Study:

  • To explore how enteric pathogens can be used as tools to study gut microbiota function.
  • To focus on metabolic pathways at the host-microbe interface during inflammation.
  • To provide conceptual insights for developing microbiota-targeting therapies.

Main Methods:

  • Experimental infection models using enteric pathogens (e.g., Salmonella enterica serovar Typhimurium).
  • Analysis of host-microbe interactions at the cellular and molecular level.
  • Focus on metabolic pathways relevant to inflammation and gut microbiota.

Main Results:

  • Enteric pathogens serve as valuable models to investigate gut microbiota dynamics during inflammation.
  • Key metabolic pathways at the host-microbe interface are highlighted.
  • Insights into cellular and molecular mechanisms governing host-microbe crosstalk during inflammation are provided.

Conclusions:

  • Studying enteric pathogens offers a unique window into gut microbiota function.
  • Understanding host-microbe metabolic interactions is vital for therapeutic strategies.
  • This knowledge can inform the rational design of novel microbiota-based treatments for inflammatory diseases.