Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dynamic Equilibrium02:20

Dynamic Equilibrium

62.6K
A reversible chemical reaction represents a chemical process that proceeds in both forward (left to right) and reverse (right to left) directions. When the rates of the forward and reverse reactions are equal, the concentrations of the reactant and product species remain constant over time and the system is at equilibrium. A special double arrow is used to emphasize the reversible nature of the reaction. The relative concentrations of reactants and products in equilibrium systems vary greatly;...
62.6K
Equation of Rotational Dynamics01:08

Equation of Rotational Dynamics

14.8K
Angular variables are introduced in rotational dynamics. Comparing the definitions of angular variables with the definitions of linear kinematic variables, it is seen that there is a mapping of the linear variables to the rotational ones. Linear displacement, velocity, and acceleration have their equivalents in rotational motion, which are angular displacement, angular velocity, and angular acceleration. Similar to the rotational variables, a mapping exists from Newton's second law of motion...
14.8K
Dynamics of Circular Motion01:30

Dynamics of Circular Motion

25.4K
An object undergoing circular motion, like a race car, is accelerating because it is changing the direction of its velocity. This centrally directed acceleration is called centripetal acceleration. This acceleration acts along the radius of the curved path (thus is also referred to as radial acceleration).
Any acceleration must be produced by some force. Therefore, any force or combination of forces can cause centripetal acceleration. A few examples include the tension in the rope on a...
25.4K
Fermi Level Dynamics01:12

Fermi Level Dynamics

719
The vacuum level denotes the energy threshold required for an electron to escape from a material surface. It is usually positioned above the conduction band of a semiconductor and acts as a benchmark for comparing electron energies within various materials.
Electron affinity in semiconductors refers to the energy gap between the minimum of its conduction band and the vacuum level and it is a critical parameter in determining how easily a semiconductor can accept additional electrons.
The work...
719
Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

2.7K
Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
2.7K
Dynamic Modulus of Elasticity of Concrete01:16

Dynamic Modulus of Elasticity of Concrete

998
The dynamic modulus of elasticity assesses how a concrete structure deforms under impact or dynamic loads. It is typically higher than the static modulus of elasticity, measured under slow, steady loading conditions.
The sonic test is a common method to determine the dynamic modulus. In this test, a concrete beam, sized either 6 x 6 x 30 inches or 4 x 4 x 20 inches, is clamped at its center. Vibrations are initiated at one end of the beam by an electromagnetic exciter unit powered by a...
998

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Research on the Similarity Law of the Fragmentation Effect of a Reactive Inner Core PELE Penetrating a Steel Plate.

Polymers·2026
Same author

Targeting 15-PGDH/15-oxoETE to mitigate inflammation and senescence in asthma.

Biochimica et biophysica acta. Molecular basis of disease·2026
Same author

The effect of zolpidem on sleep efficiency and obstructive sleep apnea severity in OSA patients: A systematic review and meta‑analysis.

Medicine·2026
Same author

The interaction network of health-related quality of life in elderly people living with HIV: a cross-sectional study in Chongqing, China.

Scientific reports·2026
Same author

Analysis of trends and risk factors of HIV incidence in men who have sex with men in Chongqing, China: a retrospective cohort study, 2013-2022.

BMC infectious diseases·2026
Same author

A multifunctional eutectogel loaded with baicalein and MXene for diabetic infected wound healing under mild photothermal conditions.

Journal of materials chemistry. B·2026

Related Experiment Video

Updated: Feb 1, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
08:28

Development of an In Vitro Ocular Platform to Test Contact Lenses

Published on: April 6, 2016

11.2K

Tear dynamics under scleral lenses.

Vivien Tse1, Bo Tan1, Young Hyun Kim2

  • 1Clinical Research Center, School of Optometry, University of California, Berkeley, United States.

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
|December 15, 2018
PubMed
Summary

Scleral lens wear shows tear exchange and mixing occurs within 20 minutes and 5 hours in healthy eyes. However, lens settling predominantly impacts post-lens tear dynamics after 5 hours, affecting about one-third of wearers.

Keywords:
Fluorescence intensityFluorogramOCTScleral lensTear exchangeTear mixing

More Related Videos

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.3K
A Novel Technique of Rescuing Capsulorhexis Radial Tear-out using a Cystotome
04:38

A Novel Technique of Rescuing Capsulorhexis Radial Tear-out using a Cystotome

Published on: January 16, 2011

13.8K

Related Experiment Videos

Last Updated: Feb 1, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
08:28

Development of an In Vitro Ocular Platform to Test Contact Lenses

Published on: April 6, 2016

11.2K
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.3K
A Novel Technique of Rescuing Capsulorhexis Radial Tear-out using a Cystotome
04:38

A Novel Technique of Rescuing Capsulorhexis Radial Tear-out using a Cystotome

Published on: January 16, 2011

13.8K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Scleral lenses are used to manage various ocular surface diseases.
  • Understanding tear dynamics under scleral lenses is crucial for optimizing lens design and patient comfort.

Purpose of the Study:

  • To evaluate post-lens tear dynamics at two different time points during scleral lens wear.
  • To compare tear exchange and lens settling effects on post-lens tear reservoir.

Main Methods:

  • Two groups of 10 neophytes each wore scleral lenses for 5 hours.
  • Post-lens tear exchange was measured using the Out-in method with FITC-Dextran.
  • Tear dynamics, fluorescence intensity, and post-lens tear thickness (PoLTT) were monitored over 5 hours.

Main Results:

  • 60-67% of subjects achieved Out-in times less than 5 minutes at 20 minutes or 5 hours.
  • 60% of tear dynamics under scleral lenses were attributed to a combination of tear exchange, mixing, and lens settling.
  • 27% of changes in post-lens tear dynamics were due to lens settling, and 13% to tear exchange and mixing.

Conclusions:

  • Tear flow into the post-lens reservoir occurs by 20 minutes and 5 hours in healthy corneas.
  • After 5 hours, approximately one-third of subjects showed no tear flow, primarily due to lens settling.
  • Lens settling significantly influences post-lens tear dynamics over extended wear periods.