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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
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Chronic thromboembolic pulmonary hypertension.
Nick H Kim1, Marion Delcroix2, Xavier Jais3
1Dept of Medicine, University of California San Diego, La Jolla, CA, USA.
The European Respiratory Journal
|December 15, 2018
Summary
Chronic thromboembolic pulmonary hypertension (CTEPH) requires specific diagnostic tests like V/Q scans and pulmonary angiograms. Treatment options include surgery, medication, or balloon angioplasty, depending on operability.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Radiology
Background:
- Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious complication of pulmonary embolism.
- CTEPH can lead to right heart failure and is a significant cause of chronic pulmonary hypertension (PH).
Purpose of the Study:
- To outline the diagnostic pathway for CTEPH.
- To describe the recommended treatment strategies for CTEPH based on patient operability.
Main Methods:
- Lung ventilation/perfusion (V/Q) scintigraphy serves as the initial screening tool.
- Pulmonary angiography and right heart catheterisation are essential for confirmation, assessment of vascular involvement, and treatment decisions.
Main Results:
- A normal V/Q scan effectively rules out CTEPH.
- Right heart catheterisation confirms PH and guides treatment determination.
Conclusions:
- Pulmonary endarterectomy is the primary recommended treatment for operable CTEPH.
- For inoperable cases, PH-targeted medical therapy (e.g., riociguat) and balloon pulmonary angioplasty are viable options.
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