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Related Experiment Video

Updated: Feb 1, 2026

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

Low back pain.

Johan W S Vlaeyen^1,2,3, Chris G Maher⁴, Katja Wiech^5,6

¹Research Group Health Psychology, University of Leuven, Leuven, Belgium. johannes.vlaeyen@kuleuven.be.

Nature Reviews. Disease Primers

|December 15, 2018

Summary

This summary is machine-generated.

Low back pain is a global health challenge with varied presentations. Recent advances in understanding psychological, social, and genetic factors are paving the way for multidisciplinary, targeted treatments.

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Area of Science:

Orthopedics
Pain Management
Rehabilitation Medicine

Background:

Low back pain (LBP) is a significant global health issue, impacting all age groups and contributing substantially to disease burden.
Despite progress, LBP management remains challenging due to its heterogeneous nature, including varied manifestations, causes, and prognoses.
Understanding the psychological, social, and genetic factors, alongside brain mechanisms, is crucial for effective LBP management.

Purpose of the Study:

To highlight the complexities in low back pain (LBP) management.
To emphasize recent advancements in understanding LBP's multifactorial nature.
To advocate for a multidisciplinary approach integrating biological, psychological, and social aspects.

Main Methods:

Review of current literature on low back pain (LBP) assessment and treatment.
Analysis of emerging research on psychological, social, genetic, and neural mechanisms of LBP.
Synthesis of findings to support a comprehensive management strategy.

Main Results:

Significant progress has been made in understanding the psychological, social, and genetic underpinnings of LBP.
New diagnostic procedures and evidence-based screening methods are being developed.
Targeted interventions are emerging, emphasizing the need for integrated care.

Conclusions:

Low back pain (LBP) management requires a multidisciplinary approach.
Integrating biological, psychological, and social factors is essential for effective LBP treatment.
Continued research into LBP's complex mechanisms will drive further advancements in care.