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Related Concept Videos

Transcription01:10

Transcription

156.3K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
156.3K
Transcription Factors02:16

Transcription Factors

82.7K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.7K
Transcription Attenuation in Prokaryotes02:42

Transcription Attenuation in Prokaryotes

18.4K
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin structure.  Bacteria use these hairpins to regulate the transcription process and control the synthesis of several amino acids including histidine, lysine, threonine, and phenylalanine. Transcription attenuation takes place in the non-coding regions of mRNA.
There are several different mechanisms used to attenuate transcription. In ribosome mediated...
18.4K
Classical Conditioning in Daily Life01:17

Classical Conditioning in Daily Life

2.2K
Classical conditioning, a fundamental principle of associative learning, explains various phenomena observed in daily life, such as fear development, the placebo effect, taste aversion, and drug habituation. These applications demonstrate the profound impact of associative learning on human behavior and physiological responses.
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
2.2K
Master Transcription Regulators02:23

Master Transcription Regulators

7.8K
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
7.8K
Eukaryotic Transcription Inhibitors01:52

Eukaryotic Transcription Inhibitors

11.0K
Certain biochemical processes, such as embryonic development and cell growth regulation, depend on the repression of specific genes. DNA binding proteins known as eukaryotic transcription inhibitors regulate the repression of gene expression in eukaryotes. The presence of these inhibitors at the required location and time in the cell is triggered by the presence of hormones and additional signals from other cells.
Eukaryotic transcription inhibitors usually contain two distinct domains, a...
11.0K

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Mapping the interview transcript: Identifying spatial policy areas from daily working practices.

Scott Orford1, Brian Webb2

  • 1School of Geography and Planning Cardiff University Wales Institute of Social and Economic Research, Data and Methods (WISERD) Cardiff UK.

Area (Oxford, England)
|December 15, 2018
PubMed
Summary
This summary is machine-generated.

Analyzing interview transcripts using geo-referencing and GIS reveals public policy practitioners

Keywords:
GISWalesinterview transcriptslocalitiesmappingspatial policy

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Area of Science:

  • Geographic Information Systems (GIS)
  • Spatial Analysis
  • Public Policy Analysis

Background:

  • Interview transcripts contain valuable geographical references often underutilized in traditional analyses.
  • Geo-referencing techniques can quantify spatial data from place names, enhancing its utility with GIS.

Purpose of the Study:

  • To present a method for analyzing and visualizing interview transcripts to determine the spatial scope of public policy practitioners' activities.
  • To explore the significance of space in public policy themes and its relation to administrative boundaries.

Main Methods:

  • Geo-referencing of place names within interview transcripts.
  • Aggregation and statistical mapping of spatial data.
  • Integration with Geographic Information System (GIS) technology.

Main Results:

  • Spatial working practices of public policy practitioners frequently extend beyond formal administrative boundaries.
  • The degree of spatial focus varies significantly across different policy themes and localities.
  • Historical geographies and the sector's devolved nature influence spatial practices.

Conclusions:

  • Mapping interview transcripts offers valuable insights beyond conventional analysis methods.
  • This approach enhances understanding of spatial dimensions in public policy.