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Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry
D C Longee1, H S Friedman, W T Djang
1Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Neurosurgery
|August 1, 1988
Abstract:
An 8-year-old boy was treated with irradiation (66 Gy) for a brain stem glioma. Five months after the completion of radiotherapy, magnetic resonance imaging demonstrated apparent tumor progression despite the patient's neurological improvement. The child continued to improve, with subsequent radiographic evidence of tumor regression, without additional therapeutic intervention. The evaluations of response and recurrence of brain tumors as well as entry criteria for Phase II studies are discussed.