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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Nursing Interventions I: Taxonomy of Nursing Interventions01:03

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Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
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Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

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Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
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Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
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Genomic Imprinting and Inheritance02:30

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
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Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
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Ultra-long Read Sequencing for Whole Genomic DNA Analysis
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Genomic Interventions in Medicine.

Oluwadurotimi S Aworunse1, Oluwatomiwa Adeniji1, Olusola L Oyesola1

  • 1Department of Biological Sciences, Covenant University, Ota, Nigeria.

Bioinformatics and Biology Insights
|December 15, 2018
PubMed
Summary

Genomics, the study of the human genome, has advanced significantly since the Human Genome Project (HGP). This field is revolutionizing clinical practice, though challenges remain, especially in Africa.

Keywords:
GenomicsHuman Genome Projectdiagnosisgene therapypersonalized medicinepharmacogenomics

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Area of Science:

  • Biomedical Sciences
  • Genomics
  • Human Genetics

Background:

  • Genomics is a rapidly advancing field studying the human genome.
  • The Human Genome Project (HGP) aimed to sequence all human DNA.
  • Genomic information offers insights into human evolution and disease.

Purpose of the Study:

  • To review key discoveries leading to the HGP.
  • To highlight major findings from the HGP.
  • To examine the impact of genomics on clinical practice and challenges in implementation.

Main Methods:

  • Literature review of milestone discoveries.
  • Analysis of Human Genome Project outcomes.
  • Discussion of genomic medicine implementation challenges.

Main Results:

  • The HGP provided a comprehensive human DNA sequence.
  • Genomics has led to new clinical applications and diagnostic tools.
  • Significant challenges exist for genomic medicine adoption, particularly in Africa.

Conclusions:

  • The HGP has transformed biomedical sciences and clinical practice.
  • Genomic medicine offers personalized healthcare approaches.
  • Addressing implementation barriers is crucial for equitable access to genomic advancements.