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Crohn's colitis-induced myocarditis
Rashad J Belin1, Ahmadreza Ghasemiesfe2, James Carr2
1Division of Cardiology, Northwestern Memorial Hospital, Chicago, IL, USA.
Insights
This case study highlights a rare instance of myocarditis developing during a Crohn's disease flare. It details the patient's journey, emphasizing atypical focal myocardial inflammation.
Area of Science:
- Cardiology
- Gastroenterology
- Immunology
Background:
- Myocarditis, inflammation of the heart muscle, can be idiopathic or secondary to systemic conditions.
- Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, can present with rare extra-intestinal manifestations like myocarditis.
- Crohn's-induced myocarditis is an uncommon complication, particularly during active disease flares.
Purpose of the Study:
- To present a unique case of a 56-year-old female with acute Crohn's colitis complicated by myocarditis.
- To delineate the clinical course and development of focal myocardial inflammation in this patient.
- To illustrate the cardiac magnetic resonance imaging (CMR) and echocardiographic findings associated with Crohn's-induced myocarditis.
Main Methods:
- Case report of a 56-year-old female patient.
- Clinical assessment during an acute Crohn's colitis exacerbation.
- Cardiac imaging including echocardiography and cardiac magnetic resonance imaging (CMR).
Main Results:
- The patient experienced an acute flare of Crohn's colitis.
- Myocarditis developed as a complication, characterized by focal myocardial inflammation with an atypical pattern.
- Cardiac imaging provided detailed findings of the myocardial inflammation.
Conclusions:
- This case underscores the rare association between Crohn's disease flares and myocarditis.
- The findings illustrate an atypical pattern of focal myocardial inflammation in Crohn's-induced myocarditis.
- Understanding these rare manifestations is crucial for comprehensive patient management.
Abstract:
Myocarditis can be idiopathic or arise in response to numerous systemic insults. Myocarditis occurring in the setting of an exacerbation of inflammatory bowel disease is a rare extra-intestinal manifestation of both ulcerative and Crohn's-related colitis. Here, we present a unique case of a 56-year-old female patient presenting with an acute Crohn's colitis flare that was eventually complicated by myocarditis. Our case is unique in that we clearly delineate the clinical course and development of myocarditis in a patient with focal myocardial inflammation in a pattern that is atypical for myocarditis. <Learning objective: To illustrate the clinical course and resolution, along with cardiac magnetic resonance imaging and echocardiographic findings, of Crohn's-induced myocarditis.>.