Cardiac erosion after catheter closure of atrial septal defect: Septal malalignment may be a novel risk factor for
Yasufumi Kijima1, Teiji Akagi2, Koji Nakagawa1
1Department of Cardiovascular Medicine, Okayama University Hospital, Okayama, Japan.
Insights
Cardiac erosion is a serious risk following atrial septal defect (ASD) closure with the Amplatzer Septal Occluder. Atrial septal malalignment may be a newly identified risk factor for this complication.
Area of Science:
- Cardiology
- Medical Devices
- Surgical Complications
Background:
- Catheter closure of atrial septal defects (ASD) is a common procedure.
- Cardiac erosion is a rare but severe complication associated with Amplatzer Septal Occluder use.
- Previous studies identified oversized devices and deficient aortic rims as risk factors.
Purpose of the Study:
- To investigate the potential role of atrial septal malalignment as a novel risk factor for cardiac erosion after ASD catheter closure.
- To discuss identified risk factors contributing to cardiac erosion.
Main Methods:
- Case report detailing pericardial tamponade after Amplatzer Septal Occluder implantation.
- Pre-procedural echocardiography (2D and 3D transesophageal) to assess anatomical features.
- Surgical confirmation of cardiac perforation.
Main Results:
- Pericardial tamponade occurred three days post-procedure.
- Echocardiography revealed a deficient aortic rim and atrial septal malalignment.
- Emergent surgery confirmed right atrial perforation into the aortic root.
- Oversized device deployment and deficient aortic rim are established risk factors.
- Atrial septal malalignment is proposed as a novel risk factor.
Conclusions:
- Cardiac erosion is a potentially lethal complication of Amplatzer Septal Occluder use in ASD closure.
- Atrial septal malalignment may represent a significant, previously unrecognized risk factor.
- Further research is needed to fully elucidate the mechanisms of cardiac erosion.
Abstract:
Pericardial tamponade occurred 3 days after the catheter closure of an atrial septal defect (ASD) using Amplatzer Septal Occluder (St. Jude Medical, St. Paul, MN, USA). Before the closure, two-dimensional and real-time three-dimensional transesophageal echocardiography demonstrated a deficient aortic rim and atrial septal malalignment. Perforation of the right atrium toward the non-coronary sinus of the aortic root was confirmed at the emergent surgery. Cardiac erosion is one of the most catastrophic complications in ASD patients undergoing catheter closure with Amplatzer Septal Occluder. Hence, several risk factors for this complication are discussed and identified. Oversized device deployment and a deficient aortic rim are accepted factors potentially causing cardiac erosion. Besides, atrial septal malalignment, which is a morphological characteristic of ASD, may be a novel risk factor for cardiac erosion. <Learning objective: Cardiac erosion is a potentially lethal complication when catheter closure of atrial septal defects using Amplatzer Septal Occluder (St. Jude Medical, St. Paul, MN, USA) is provided to the patients. However, mechanisms of this complication remain to be completely elucidated. Atrial septal malalignment may be one of the novel risk factors for this catastrophic complication.>.
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