Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vesicular Tubular Clusters01:45

Vesicular Tubular Clusters

3.2K
After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi.
With the help of motor proteins such...
3.2K
Tubular Reabsorption and Secretion01:28

Tubular Reabsorption and Secretion

6.7K
Tubular secretion and reabsorption are two critical processes in the nephron tubule of the kidneys. When the fluid filtered from the glomerulus enters the proximal convoluted tubule, it is referred to as filtrate, and its composition changes due to tubular reabsorption and secretion.
Tubular reabsorption is a selective process that starts when the filtrate enters the proximal tubules. It involves substances traveling through the transcellular route (through the tubule cell and peritubular...
6.7K
What is Genetic Engineering?00:49

What is Genetic Engineering?

80.2K
Overview
80.2K
Renal Drug Excretion: Tubular Reabsorption01:25

Renal Drug Excretion: Tubular Reabsorption

845
Tubular reabsorption, a process occurring post-glomerular filtration of drugs in the renal tubule, is a critical determinant of drug half-life. During the process of renal excretion, as the glomerular filtrate progresses to the distal convoluted tubule (DCT), drugs that are highly permeable, lipophilic, and nonionized undergo passive reabsorption from the tubular fluid into the surrounding peritubular capillaries. This reabsorption process restricts their elimination through the kidneys. This...
845
Renal Drug Excretion: Tubular Secretion01:28

Renal Drug Excretion: Tubular Secretion

877
Active tubular secretion is a robust, energy-demanding process that utilizes carrier systems to transport drugs into renal tubules. The active renal secretion systems include the organic anion transporter (OAT) for weak acids and the organic cation transporter (OCT) for weak bases. Structurally similar drugs can compete for the same transporter, potentially leading to drug accumulation and toxicity. However, this principle can be exploited therapeutically. One example is probenecid (Probalan),...
877
Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion01:22

Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion

1.3K
The kidneys maintain homeostasis through filtration, reabsorption, and secretion. Tubular reabsorption and secretion are crucial in forming urine and regulating electrolytes, water balance, and waste elimination.Tubular Reabsorption and Secretion ProcessesTubular reabsorption is the process that reclaims essential substances such as electrolytes, glucose, amino acids, and water from the glomerular filtrate back into the bloodstream. This is achieved through passive and active transport...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Constrained Layer Damping Perspective on Floating Floor Systems for Low-Frequency Impact Noise Control.

Polymers·2026
Same author

The association of remnant cholesterol inflammatory index with the risk of major adverse cardiovascular events in patients with angina undergoing percutaneous coronary intervention: a retrospective study.

Frontiers in cardiovascular medicine·2026
Same author

Maxillary sinus-related adverse event reports associated with endosseous dental implants in the FDA MAUDE database: a retrospective text-mining analysis.

BMC oral health·2026
Same author

Synergistic modulation of composite donors and π-spacers in porphyrin sensitizers for enhanced charge transfer and photovoltaic efficiency: a DFT/TD-DFT study.

Physical chemistry chemical physics : PCCP·2026
Same author

Epidemiological characteristics of varicella in Xuzhou from 2015 to 2024: surveillance study.

BMC infectious diseases·2026
Same author

2-guanidine-4-methylquinazoline inhibits platelet activation and thrombosis by targeting the acid-sensing ion channel 3.

European journal of pharmacology·2026

Related Experiment Video

Updated: Feb 1, 2026

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.9K

3D biofabrication for tubular tissue engineering.

Ian Holland1, Jack Logan1, Jiezhong Shi1,2

  • 11Department of Biomedical Engineering, University of Strathclyde, Glasgow, G1 1QE UK.

Bio-Design and Manufacturing
|December 15, 2018
PubMed
Summary

Tissue engineering offers solutions for tubular tissue replacement, overcoming limitations of current prostheses. Advanced 3D bioprinting techniques are crucial for developing artificial tubular tissues with enhanced therapeutic potential.

Keywords:
3D printingBio-inksTissue engineeringTubular organs

More Related Videos

Tissue Engineering of a Human 3D in vitro Tumor Test System
11:12

Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

21.8K
3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue
08:57

3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue

Published on: July 16, 2021

7.1K

Related Experiment Videos

Last Updated: Feb 1, 2026

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.9K
Tissue Engineering of a Human 3D in vitro Tumor Test System
11:12

Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

21.8K
3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue
08:57

3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue

Published on: July 16, 2021

7.1K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Therapeutic replacement of diseased tubular tissue faces limitations due to donor availability and prosthesis suitability.
  • Tissue-engineered constructs offer potential solutions with reduced immune response and improved anatomical accuracy.
  • 3D bioprinting technology presents new opportunities for biofabrication and therapeutic applications.

Purpose of the Study:

  • To review the challenges in creating artificial tubular tissue with complex architectures.
  • To examine current biofabrication approaches, including 3D printing techniques.
  • To suggest future directions for artificial tubular tissue development.

Main Methods:

  • Review of existing literature on tissue engineering and biofabrication.
  • Analysis of 3D printing technologies applied to tubular tissue constructs.
  • Discussion of challenges in macro- and microscopic architectural replication.

Main Results:

  • Current prostheses have limitations in availability and suitability for tubular tissue replacement.
  • Tissue engineering and 3D bioprinting show promise for creating functional artificial tubular tissues.
  • Complex macro- and microscopic architecture remains a significant challenge.

Conclusions:

  • Tissue engineering, particularly with 3D bioprinting, holds significant potential for tubular tissue replacement.
  • Addressing architectural complexities is key to advancing artificial tubular tissue development.
  • Further research into biofabrication techniques is needed to realize the full therapeutic potential.