Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Embryonic Stem Cells00:58

Embryonic Stem Cells

32.4K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.4K
Embryonic Stem Cells00:57

Embryonic Stem Cells

5.0K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
5.0K
Embryonic Connective Tissues01:20

Embryonic Connective Tissues

6.5K
During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development.
6.5K
Assessment of the Mouth01:26

Assessment of the Mouth

1.2K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.2K
Assessment of Respiration01:23

Assessment of Respiration

2.0K
The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
2.0K
Nursing Assessment01:29

Nursing Assessment

9.4K
The two sources for collecting information are primary and secondary. After gathering information, interpretation and validation help to complete the data. The purpose of assessment is to establish data with the initial information, to interpret data about the patient's perceived needs and health problems, and to respond to these problems identified.
The nurse collects all aspects of the patient's health in the initial assessment, establishing priorities for ongoing focused assessments...
9.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D-printed biodegradable films for antimicrobial and antioxidant active packaging: application in grape preservation.

Food chemistry·2026
Same author

MXene-AuNP electrochemical aptasensor for dual-channel detection of insulin and glucose with HOMA-IR quantification.

Biosensors & bioelectronics·2026
Same author

Rapid Colorimetric Detection of Inorganic Phosphate in Eutrophic Waters via Proton-Coupled Electron Transfer in Quinhydrone.

Analytical chemistry·2026
Same author

Notch receptors involved in the choice between intestinal secretory and enterocytes and differentiation of Bestrophin 4 cells.

bioRxiv : the preprint server for biology·2025
Same author

Integrating AI with Biosensors and Voltammetry for Neurotransmitter Detection and Quantification: A Systematic Review.

Biosensors·2025
Same author

Engineering high-affinity and selective molecular recognition redox active imprinted platform on carbon cloth for electrochemical sensing of aflatoxin B1 in milk samples.

Food chemistry·2025

Related Experiment Video

Updated: Feb 1, 2026

Immunostaining of Dissected Zebrafish Embryonic Heart
06:23

Immunostaining of Dissected Zebrafish Embryonic Heart

Published on: January 10, 2012

18.3K

Nanotoxicity Assessment Using Embryonic Zebrafish.

Eduard Dumitrescu1, Kenneth Wallace2, Silvana Andreescu3

  • 1Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY, USA.

Methods in Molecular Biology (Clifton, N.J.)
|December 15, 2018
PubMed
Summary

A new method using zebrafish embryos can assess the toxicity of various nanomaterials. This approach helps evaluate risks from nano-enabled products in the environment, determining lethal and sublethal effects.

Keywords:
ApoptosisHistologyNanomaterialsNanoparticlesNanotoxicityOxidative stressViability assayZebrafish embryos

More Related Videos

An Assay for Permeability of the Zebrafish Embryonic Neuroepithelium
06:37

An Assay for Permeability of the Zebrafish Embryonic Neuroepithelium

Published on: October 24, 2012

9.9K
Microdissection of Zebrafish Embryonic Eye Tissues
09:01

Microdissection of Zebrafish Embryonic Eye Tissues

Published on: June 27, 2010

16.7K

Related Experiment Videos

Last Updated: Feb 1, 2026

Immunostaining of Dissected Zebrafish Embryonic Heart
06:23

Immunostaining of Dissected Zebrafish Embryonic Heart

Published on: January 10, 2012

18.3K
An Assay for Permeability of the Zebrafish Embryonic Neuroepithelium
06:37

An Assay for Permeability of the Zebrafish Embryonic Neuroepithelium

Published on: October 24, 2012

9.9K
Microdissection of Zebrafish Embryonic Eye Tissues
09:01

Microdissection of Zebrafish Embryonic Eye Tissues

Published on: June 27, 2010

16.7K

Area of Science:

  • Environmental Science
  • Toxicology
  • Biotechnology

Background:

  • Nanomaterials are increasingly present in consumer products and the environment.
  • Assessing nanomaterial toxicity is challenging due to their diverse properties.
  • Zebrafish embryos offer advantages for high-throughput toxicity screening.

Purpose of the Study:

  • To describe a methodology for assessing nanomaterial toxicity.
  • To evaluate potential risks posed by nanomaterials to living organisms.
  • To establish a universal screening approach for nanomaterial safety.

Main Methods:

  • Utilizing zebrafish embryos as a model organism.
  • Employing high-throughput screening for toxicity assessment.
  • Evaluating lethal (LD50) and sublethal effects, including morphological defects, apoptosis, and reactive species production.

Main Results:

  • The described methodology provides a universal screening approach for nanomaterial toxicity.
  • The method allows for the determination of lethal doses (LD50).
  • Sublethal effects such as organ defects and cellular damage can be quantified.

Conclusions:

  • Zebrafish embryos are a suitable model for high-throughput nanomaterial toxicity assessment.
  • This methodology enables comprehensive evaluation of nanomaterial risks.
  • The approach can inform safety assessments of nano-enabled products.