Mapping theme trends and knowledge structure on adipose-derived stem cells: a bibliometric analysis from 2003 to 2017

Area of Science:

• Biomedical research
• Stem cell biology
• Regenerative medicine

Background:

• Adipose-derived stem cells (ADSCs) are crucial in regenerative medicine.
• Understanding ADSC research trends is vital for future development.
• Bibliometric analysis provides insights into scientific literature evolution.

Purpose of the Study:

• To map the theme trends and knowledge structure of ADSC literature.
• To identify evolving research topics and emerging hot spots in ADSC research.
• To provide a basis for future ADSC-related research directions.

Main Methods:

• Bibliometric analysis was employed.
• Co-word analysis was utilized to identify thematic relationships.
• Strategic diagrams and social network analysis mapped research evolution and hot spots.

Main Results:

• ADSC research themes evolved from differentiation and transplantation (2003-2007) to regenerative medicine and myocardial infarction (2008-2012).
• Further shifts occurred towards miRNA in ADSC genetics and nerve regeneration (2013-2017).
• Emerging hot spots included regenerative medicine, myocardial infarction therapy, miRNA genetics, and nerve regeneration physiology.

Conclusions:

• The identified emerging hot spots represent potential new research avenues.
• Understanding these trends can guide future investigations in ADSC applications.
• This bibliometric study highlights the dynamic nature of ADSC research.