Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Membrane Proteins01:16

Introduction to Membrane Proteins

81.1K
The cell membrane, or plasma membrane, is an ever-changing landscape. It is described as a fluid mosaic where various macromolecules are embedded in the phospholipid bilayer. Among the macromolecules are proteins. The protein content varies across cell types. For example, mitochondrial inner membranes contain ~76% protein content, while myelin contains ~18% protein content. Individual cells contain many types of membrane proteins—red blood cells contain over 50—and different cell...
81.1K
What are Membranes?01:54

What are Membranes?

190.5K
A key characteristic of life is the ability to separate the external environment from the internal space. To do this, cells have evolved semi-permeable membranes that regulate the passage of biological molecules. Additionally, the cell membrane defines a cell’s shape and interactions with the external environment. Eukaryotic cell membranes also serve to compartmentalize the internal space into organelles, including the endomembrane structures of the nucleus, endoplasmic reticulum and...
190.5K
What are Membranes?01:24

What are Membranes?

18.9K
A cell's plasma membrane demarcates the cell's borders and determines the nature of its interaction with the environment. Cells exclude certain substances, take in others, and excrete some others in controlled quantities. The plasma membrane must be flexible to allow certain cells, such as red and white blood cells, to change their shape while passing through narrow capillaries. These are the more obvious plasma membrane functions. In addition, the plasma membrane's surface carries...
18.9K
The Resting Membrane Potential01:21

The Resting Membrane Potential

142.5K
Overview
142.5K
Membrane Fluidity01:23

Membrane Fluidity

174.1K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
174.1K
Membrane Lipids01:32

Membrane Lipids

34.2K
Lipids are an essential component of all biological membranes. The average lipid content in mammalian membranes is 50%, though it can be as low as 20% in the inner mitochondrial membrane or as high as 80% in the myelin sheath present around the nerve cells.
Phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin are the most common phospholipids present in mammalian membranes. At physiological pH, phosphatidylserine is negatively charged, while the other three...
34.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical and Transcatheter Tricuspid Valve Interventions: An Electrophysiology-Focused Review.

Journal of cardiovascular development and disease·2026
Same author

Lifetime Management of Aortic Stenosis: Evolving Strategies and Personalized Decision-Making.

Journal of clinical medicine·2026
Same author

Poor Agreement Between Intraoperative Transesophageal Echocardiography and Postoperative Transthoracic Echocardiography for Transmitral Mean Pressure Gradient After Mitral Valve Repair.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Association of the cardiovascular-kidney-metabolic syndrome and adverse outcomes after noncardiac surgery.

British journal of anaesthesia·2025
Same author

Retrieval of an Embolized Left Atrial Appendage Occluder From the Aortic Arch Using a Transcatheter Retrieval Device.

JACC. Case reports·2025
Same author

Dual Orexin Receptor Antagonists for Delirium: A Scoping Review and Feasibility Trial of Daridorexant.

Journal of the Academy of Consultation-Liaison Psychiatry·2025
Same journal

Thoracotomy Versus Uniportal and Multiportal Video-Assisted Thoracoscopic Approaches for Lymph Node Dissection in Lung Cancer: A Propensity-Matched Analysis.

Innovations (Philadelphia, Pa.)·2026
Same journal

Robot-Assisted Coronary Artery Bypass Versus Percutaneous Coronary Intervention in Patients With Coronary Artery Disease: A Meta-Analysis.

Innovations (Philadelphia, Pa.)·2026
Same journal

Robot-Assisted Cardiac Surgery in Carney-Stratakis Syndrome: A New Frontier in Tumor Resection.

Innovations (Philadelphia, Pa.)·2026
Same journal

COR-KNOT Repair of Iatrogenic Tracheal Injury During VATS Right Upper Lobectomy in a 65-Year-Old Female Patient.

Innovations (Philadelphia, Pa.)·2026
Same journal

Incidence of Permanent Pacemaker Implantation Following Tricuspid Valve Surgeries: A Systematic Review and Meta-Analysis.

Innovations (Philadelphia, Pa.)·2026
Same journal

Modified Right Vertical Infra-Axillary Thoracotomy Technique: A 2 to 5 cm Incision Approach for Repair of Various Congenital Heart Diseases in All Age Groups.

Innovations (Philadelphia, Pa.)·2026
See all related articles

Related Experiment Video

Updated: Feb 1, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

12.3K

Right Mini-Thoracotomy Subaortic Membrane Resection.

Carl A Johnson1, Juan A Siordia, Davida A Robinson

  • 1From the Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, NY USA.

Innovations (Philadelphia, Pa.)
|December 15, 2018
PubMed
Summary
This summary is machine-generated.

Minimally invasive mini-thoracotomy effectively resects subaortic membranes, offering an alternative to sternotomy. This approach shows excellent clinical outcomes for patients with discrete subaortic stenosis.

More Related Videos

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

940
Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications
04:43

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications

Published on: March 15, 2024

1.5K

Related Experiment Videos

Last Updated: Feb 1, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

12.3K
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

940
Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications
04:43

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications

Published on: March 15, 2024

1.5K

Area of Science:

  • Cardiovascular Surgery
  • Minimally Invasive Cardiac Surgery

Background:

  • Subaortic membrane causes discrete subaortic stenosis and aortic insufficiency.
  • Median sternotomy is the traditional approach for subaortic membrane resection.
  • Minimally invasive techniques may offer benefits for patients requiring this procedure.

Purpose of the Study:

  • To evaluate the initial clinical experience of subaortic membrane resection using a mini-thoracotomy approach in adult patients.
  • To assess the feasibility and outcomes of this minimally invasive technique.

Main Methods:

  • Retrospective review of eight adult patients undergoing elective subaortic membrane resection via mini-thoracotomy.
  • Procedure involved a 5-cm incision, video assistance, cardiopulmonary bypass, and resection with specialized instruments.
  • Key outcomes evaluated included operative times, length of stay, ventilation time, and postoperative morbidity.

Main Results:

  • Median cardiopulmonary bypass and cross-clamp times were 60 and 42 minutes, respectively.
  • Median extubation time was 3.6 hours, with short intensive care unit (22 hours) and hospital stays (3 days).
  • Significant reduction in left ventricular outflow tract mean gradients (26.5 to 9.4 mm Hg) and no 30-day mortality or conversions to sternotomy were observed.

Conclusions:

  • Subaortic membrane resection can be safely and effectively performed through a mini-thoracotomy approach.
  • This minimally invasive technique yields excellent clinical results, comparable to traditional methods.
  • Mini-thoracotomy represents a viable alternative for selected patients needing subaortic membrane resection.