Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

6.7K
The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
6.7K
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

3.7K
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
3.7K
Areas Within Irregular Boundaries01:26

Areas Within Irregular Boundaries

382
Calculating areas within irregular boundaries, such as along rivers or curved roads, is crucial in various fields, including surveying, engineering, and environmental management. Surveyors often begin by creating a traverse, a connected series of straight lines approximating the area's boundary. The coordinates of each traverse point are essential for calculating the enclosed area. The double meridian distance formula is a widely used technique for this purpose. This method utilizes the...
382
Electrostatic Boundary Conditions01:16

Electrostatic Boundary Conditions

964
Consider an external electric field propagating through a homogeneous medium. When the electric field crosses the surface boundary of the medium, it undergoes a discontinuity. The electric field can be resolved into normal and tangential components. The amount by which the field changes at any boundary is given by the difference between the field components above and below the surface boundary.
The surface integral of an electric field is given by Gauss's law in integral form and is related to...
964
Magnetostatic Boundary Conditions01:28

Magnetostatic Boundary Conditions

1.7K
An electric field suffers a discontinuity at a surface charge. Similarly, a magnetic field is discontinuous at a surface current. The perpendicular component of a magnetic field is continuous across the interface of two magnetic mediums. In contrast, its parallel component, perpendicular to the current, is discontinuous by the amount equal to the product of the vacuum permeability and the surface current. Like the scalar potential in electrostatics, the vector potential is also continuous...
1.7K
Boundary Layer Characteristics01:18

Boundary Layer Characteristics

616
When a fluid encounters a solid surface, a boundary layer forms due to the interaction between the fluid's motion and the stationary surface. This phenomenon is characterized by a thin region adjacent to the surface where viscous forces dominate, influencing the fluid's velocity profile. The development of the boundary layer begins at the leading edge of the surface and evolves as the fluid moves downstream.As the fluid flows over the surface, friction between the fluid and the wall slows down...
616

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tbx16 and mesogenin 1 promote presomitic mesoderm differentiation by repressing the mesodermal progenitor cell state.

PLoS genetics·2026
Same author

JCAD couples tight junction condensates to actin and RhoA to maintain the endothelial barrier.

bioRxiv : the preprint server for biology·2026
Same author

<i>Eed</i> controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.

eLife·2025
Same author

Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion.

The Journal of cell biology·2025
Same author

A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis.

Development (Cambridge, England)·2022
Same author

EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts.

The Journal of cell biology·2021

Related Experiment Video

Updated: Feb 1, 2026

Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

12.5K

Cellular organization and boundary formation in craniofacial development.

Abigail A Kindberg1, Jeffrey O Bush1

  • 1Department of Cell and Tissue Biology, Program in Craniofacial Biology, and Institute of Human Genetics, University of California at San Francisco, San Francisco, California.

Genesis (New York, N.Y. : 2000)
|December 15, 2018
PubMed
Summary

Cellular self-organization drives craniofacial development. Understanding boundary formation mechanisms is key to preventing congenital anomalies.

Keywords:
CraniofacialEphboundarycadherincell migrationcell sortingephrinneural crestrhombomere

More Related Videos

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
09:25

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development

Published on: March 24, 2011

9.9K
Assessing Species-specific Contributions To Craniofacial Development Using Quail-duck Chimeras
09:38

Assessing Species-specific Contributions To Craniofacial Development Using Quail-duck Chimeras

Published on: May 31, 2014

11.4K

Related Experiment Videos

Last Updated: Feb 1, 2026

Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

12.5K
Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
09:25

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development

Published on: March 24, 2011

9.9K
Assessing Species-specific Contributions To Craniofacial Development Using Quail-duck Chimeras
09:38

Assessing Species-specific Contributions To Craniofacial Development Using Quail-duck Chimeras

Published on: May 31, 2014

11.4K

Area of Science:

  • Developmental Biology
  • Cellular Biology
  • Regenerative Medicine

Background:

  • Craniofacial morphogenesis involves dynamic cellular changes for structure formation.
  • Boundary formation is crucial for cellular organization, patterning, and tissue separation.
  • Disruptions in boundary formation can lead to craniofacial congenital anomalies.

Purpose of the Study:

  • To review boundary formation mechanisms in craniofacial development.
  • To highlight cellular behaviors and self-organizing properties critical for morphogenesis.
  • To connect boundary formation to craniofacial congenital anomalies.

Main Methods:

  • Review of existing literature on craniofacial development and boundary formation.
  • Analysis of cellular mechanisms including transcriptional patterning, cell segregation, adhesion, and migration.
  • Focus on self-organizing principles in cellular behavior.

Main Results:

  • Boundary formation relies on multiple cellular mechanisms for proper tissue organization.
  • Self-organizing properties of cells are fundamental to craniofacial morphogenesis.
  • Aberrant boundary formation directly impacts craniofacial structure and development.

Conclusions:

  • Understanding cellular self-organization in boundary formation is vital for craniofacial development.
  • This knowledge can inform strategies for preventing or treating craniofacial congenital anomalies.
  • Further research into these mechanisms holds potential for regenerative medicine applications.