Related Experiment Video
Updated: Feb 1, 2026

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
Published on: March 15, 2019
Genome sequence of Methylocystis hirsuta CSC1, a polyhydroxyalkanoate producing methanotroph
Sergio Bordel1,2, Elisa Rodríguez1,2, Raúl Muñoz1,2
1Departamento de Ingeniería Química y Tecnología del Medio Ambiente, Escuela de Ingenierías Industriales, Universidad de Valladolid, Valladolid, Spain.
Abstract:
Polyhydroxyalkanoates (PHAs) are biodegradable plastics that can be produced by some methanotrophic organisms such as those of the genus Methylocystis. This allows the conversion of a detrimental greenhouse gas into an environmentally friendly high added-value bioproduct. This study presents the genome sequence of Methylocystis hirsuta CSC1 (a high yield PHB producer). The genome comprises 4,213,043 bp in 4 contigs, with the largest contig being 3,776,027 bp long. Two of the other contigs are likely to correspond to large size plasmids. A total of 4,664 coding sequences were annotated, revealing a PHA production cluster, two distinct particulate methane monooxygenases with active catalytic sites, as well as a nitrogen fixation operon and a partial denitrification pathway.
Related Concept Videos
Genomics
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Genome Size and the Evolution of New Genes
Cis-regulatory Sequences
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes
Sequences

