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Related Experiment Video

Updated: Feb 1, 2026

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Published on: July 3, 2025

Graphene Oxide as an Optical Biosensing Platform: A Progress Report.

Eden Morales-Narváez¹, Arben Merkoçi^2,3

¹Biophotonic Nanosensors Laboratory, Centro de Investigaciones en Óptica, A. C., Loma del Bosque 115, Lomas del Campestre, León, Guanajuato, 37150, México.

Advanced Materials (Deerfield Beach, Fla.)

|December 15, 2018

Summary

Graphene oxide (GO) properties significantly impact optical biosensing. New methods integrate GO onto solid phases, advancing biosensor technology beyond colloidal suspensions.

Keywords:

2D materials bioanalytical applications label-free biosensors optical devices physicochemical properties

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Area of Science:

Materials Science
Nanotechnology
Biomedical Engineering

Background:

Graphene oxide (GO) properties like C/O ratio and layer number were poorly understood regarding their effect on optical biosensing.
Early GO biosensors primarily used colloidal suspensions, limiting integration and device design.

Purpose of the Study:

To critically review the influence of GO physicochemical properties on optical biosensing.
To highlight advancements in GO integration onto solid phases for novel biosensing devices.
To explore emerging label-free optical techniques for GO-based biosensing.

Main Methods:

Literature review focusing on graphene oxide properties and their impact on biosensing performance.
Analysis of new approaches for solid-phase GO integration in biosensors.
Examination of photoluminescent and label-free optical detection methods (SPR, SERS, optical fibers).

Main Results:

Significant progress has been made in understanding GO features crucial for optical biosensing.
Novel strategies now enable solid-phase GO integration, moving beyond colloidal suspensions.
Label-free optical techniques, including SPR and SERS, show great promise for GO biosensors.

Conclusions:

Physicochemical properties of graphene oxide are pivotal for advanced optical biosensing.
Solid-phase integration and label-free techniques represent key future directions for GO biosensors.
The field presents numerous opportunities for developing innovative and high-performance biosensing platforms.