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In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
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Repair Versus Replacement of Restorations.

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    This summary is machine-generated.

    Dentists regularly assess dental restorations for defects. This review covers criteria and methods for repairing, refurbishing, or replacing restorations, aiding clinical decision-making.

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    Area of Science:

    • Restorative Dentistry
    • Dental Materials Science

    Background:

    • Dental restorations frequently exhibit defects.
    • Evaluating restoration integrity is a daily dental practice.

    Purpose of the Study:

    • To review criteria for determining restoration repair, refurbishment, or replacement.
    • To discuss methods and materials for dental restoration repair.

    Main Methods:

    • Literature review of restorative dentistry principles.
    • Analysis of decision-making criteria for restoration management.

    Main Results:

    • Established criteria for assessing restoration acceptability.
    • Identified various repair and refurbishment techniques.
    • Discussed the scientific basis for clinical decisions.

    Conclusions:

    • Clinical decisions regarding restorations should be evidence-based.
    • Repair and refurbishment are viable alternatives to replacement in many cases.
    • Understanding material science aids in effective restoration management.