Related Experiment Video
Updated: Feb 1, 2026

08:31
Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
Published on: July 31, 2016
14.5K
LOH (late-onset hypogonadism) syndrome
Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 15, 2018
Summary
Testosterone deficiency in aging men is common. Low free testosterone levels (below 8.5 pg/mL) indicate a need for testosterone replacement therapy, but treatment options in Japan are limited.
Area of Science:
- Endocrinology
- Geriatrics
- Men's Health
Background:
- Testosterone deficiency is increasingly recognized in aging men, presenting with hypogonadal symptoms.
- Late-onset hypogonadism (LOH) affects a significant portion of the aging male population.
- Testosterone replacement therapy (TRT) has shown potential benefits for LOH syndrome.
Purpose of the Study:
- To evaluate the diagnostic threshold for serum free testosterone in the Japanese population for TRT indication.
- To discuss current therapeutic limitations for LOH syndrome in Japan.
Main Methods:
- Analysis of age-specific serum testosterone concentration data.
- Identification of a serum free testosterone threshold indicative of LOH.
Main Results:
- Serum free testosterone levels below 8.5 pg/mL are suggested as an indicator for TRT in Japanese men.
- Testosterone enanthate is currently the sole TRT option covered by Japanese health insurance.
Conclusions:
- A specific serum free testosterone level can guide TRT decisions in the Japanese aging male population.
- Current insurance coverage in Japan limits treatment choices for LOH syndrome, necessitating further research for optimal management.
Related Concept Videos
Nephrotic Syndrome I : Introduction
633
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
633
Acute Coronary Syndrome I: Introduction
990
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
990
Irritable Bowel Syndrome I: Introduction
1.0K
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.0K
Restless Leg Syndrome and Night Terrors
560
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
560
Acute Coronary Syndrome V: Nursing Management
325
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
325
Nephrotic Syndrome II : Assessment and Medical Management
239
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
239

