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Updated: Feb 1, 2026

In Vitro Analysis of Myd88-mediated Cellular Immune Response to West Nile Virus Mutant Strain Infection
Published on: November 27, 2014
West Nile fever/Neuroinvasive disease caused by WNV
Abstract:
West Nile virus (WNV) is a mosquito-borne flavivirus that invaded New York City in 1999 and quickly spread and settled in all 48 contiguous United States and all 10 Canadian provin- ces. WNV is still expanding its territory and is now headed towards Latin American coun- tries. Neuroinvasive disease caused by WNV develops in less than 1% of the affected popula- tion, but its mortality rate is approximately 10%. An imported WNV infection case occurred in Japan in 2005. Reservoir birds and mosquito vectors for WNV infection cycle are existing in Japan. Thus, we need to be cautious for a possible invasion of WNV in Japan.
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