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Normal axillary thickness thresholds as a metric for nutritional status of children
Alissa L Wall Kleinhenz1, Jing Gao2, Arzu Kovanlikaya3
1University of Michigan Medical School, Taubman Health Sciences Library, 1135 Catherine St, Ann Arbor, MI 48109, United States of America.
Insights
Axillary thickness is a simple, effective indicator for detecting malnutrition in children. A threshold of 1.5 cm can help identify undernourishment, aiding in childhood pneumonia management.
Area of Science:
- Pediatric Medicine
- Nutritional Assessment
- Medical Imaging
Background:
- Childhood pneumonia is a leading cause of mortality in developing nations.
- Undernourishment exacerbates childhood pneumonia severity.
- Axillary thickness offers a simple method for nutritional status evaluation alongside lung ultrasound.
Purpose of the Study:
- To determine axillary thickness distribution in children.
- To establish a threshold for identifying malnutrition.
- To assess the utility of axillary thickness in conjunction with lung ultrasound for pneumonia.
Main Methods:
- Retrospective analysis of chest CT scans in children aged 0-5 years without debilitating disease.
- Bilateral axillary thicknesses measured and segmented by age, sex, and laterality.
- Statistical analysis using ANOVA and 5th percentile to determine lower bound thresholds.
Main Results:
- 247 scans met inclusion criteria; ANOVA showed no significant differences across groups (p=0.377).
- A 1.5 cm axillary thickness was identified as a general threshold for malnutrition detection.
- A 1.1 cm threshold may be necessary for males aged 0-1 years.
Conclusions:
- A uniform axillary thickness threshold of 1.5 cm is proposed for malnutrition assessment in children.
- This finding supports using axillary thickness during lung ultrasound for childhood pneumonia.
- Axillary thickness provides a practical, non-invasive nutritional marker.
Introduction:
Childhood pneumonia is a major cause of death in the 3rd world, and undernourishment increases the severity of the condition. We considered axillary thickness as a simple measurement to evaluate nutritional status that can be performed simultaneously with lung ultrasound. Our goal was to determine the distribution of axillary thickness in a cohort of children to determine a threshold for malnutrition.
Methods:
Clinical databases were scanned to identify chest computed tomograms (CT) in children between the ages of 0 and 5 years with non-debilitating disease. The bilateral axillary thicknesses of the cohort were determined using equivalent width, and these measurements were segmented by age, sex, and laterality to determine cutoff thresholds. Data was evaluated using single factor analysis of variance (ANOVA) and 5th percentile analysis to determine the lower bound thresholds of axillary thickness.
Results:
247 scans met inclusion criteria. ANOVA demonstrated no significant differences in the mean measurements in the 5 groups (p = 0.377). 95% confidence limits on the 5th percentile plots showed an axillary thickness of 1.5 cm was a reasonable threshold for malnutrition detection for all age groups and sexes except for males between 0 and 1 years old where a 1.1 cm threshold may be required.
Discussion:
CT scans of the chests in a cohort of children without debilitating disease revealed a remarkably uniform axillary thickness threshold for malnutrition assessment of 1.5 cm. This suggests that there may be a threshold for nutritional assessment for children undergoing lung ultrasound scans for childhood pneumonia.
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