Related Experiment Video
Updated: Feb 1, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Severe intractable asthma
Abstract:
Severe persistent asthma has been defined as being symptomatic every day with distur- bance of daily life. To judge asthma as severe and intractable, besides misdiagnosis, treatment step 4 has been properly done with good adherence, appropriate management of comorbidi- ties, avoidance of risk factors. Management for severe intractable asthma consists of thera- peutic step 4 with adjustment of the dose of sustained release theophylline by a step-wise manner with therapeutic dose monitoring, and selection of ICS or ICS/LABA considering individual state, and selecting intermittent administration of OCS and/or anti-IgE(omali- zumab) or anti-IL-5 (mepolizumab) antibodies after getting informed consent from a patient.
Related Concept Videos
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-IV: Nursing Management
First, in...

