Related Experiment Videos
Current concepts of the pathogenesis of optic neuritis associated with multiple sclerosis
1Wills Eye Hospital Neuro-Ophthalmology Service, University of Pennsylvania School of Medicine, Philadelphia.
Survey of Ophthalmology
|September 1, 1988
Abstract:
Optic neuritis may occur as an isolated entity or as a manifestation of multiple sclerosis (MS), a widespread central nervous system demyelinating disease. Clinical, electrophysiological, magnetic resonance imaging and neuropathologic data support the hypothesis that "idiopathic" optic neuritis represents a restricted form of MS. The current evidence for viral, cell mediated, and antibody-induced etiologies of MS and optic neuritis are reviewed.