Related Experiment Video
Updated: Feb 1, 2026

Basic Methods for the Study of Reproductive Ecology of Fish in Aquaria
Published on: July 20, 2017
Immunohistochemical Study of Four Fish Tumors
1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, via F. Stagno d'Alcontres 31, University of Messina, 98165, Messina, Italy.
Abstract:
The present study supports the usefulness of ancillary techniques, such as immunohistochemistry, as a valid diagnostic tool in the field of fish oncology. The immunohistochemical patterns observed in four neoplasms on four individual teleosts belonging to different species are described. Cytokeratin, vimentin, actin, S100, calretinin, and Melan-A antibodies were used. Diagnoses of papilloma in a Bream Abramis brama, fibroma in a Sand Steenbras Lithognathus mormyrus, schwannoma in a Crucian Carp Carassius carassius, and melanoma in a spontaneously inbred Xiphophorus hybrid were made. Diagnosis of tumors in fish is not always easy to carry out, and the tool provided by antibodies used on mammalian tissue is essential for obtaining definitive, unambiguous, and inexpensive identification.
Related Concept Videos
Osmoregulation in Fishes
FISH - Fluorescent In-situ Hybridization
Tumor Immunotherapy
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
The Tumor Microenvironment
Case Studies

