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Updated: Feb 1, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Factors associated with decision to undergo contralateral prophylactic mastectomy versus unilateral mastectomy
1Department of Surgery, Yale University School of Medicine, 20 York Street, 1st Floor, Suite A, New Haven, CT, 06510, USA.
Background:
Factors associated with the decision to pursue unilateral mastectomy (UM) versus contralateral prophylactic mastectomy (CPM) in unilateral breast cancer (UBC) patients, and satisfaction with this decision, remain to be elucidated.
Methods:
UBC patients who underwent mastectomy were surveyed regarding factors affecting their surgical decision and satisfaction with the same.
Results:
Both UM (n = 46) and CPM (n = 55) patients were satisfied with their surgical decision (mean 4.72 and 4.85 out of 5 on Satisfaction With Decision scale, respectively, p = 0.078). Most CPM patients cited the desire to lower their risk of contralateral breast cancer (96.4%) and the desire for peace of mind (94.5%) as "very important" drivers of their decision; whereas most UM patients felt not wanting to remove a normal breast (67.4%) was a "very important" driver for their decision.
Conclusions:
Both UM and CPM patients reported high satisfaction with their surgical decisions, despite differing reasons for their respective surgeries.
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