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Updated: Jan 31, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Idiopathic macular telangiectasia type 2: A six-year study with multimodal imaging of a presumed unilateral case
Mohammad Zarei1, Mehdi Mazloumi1, Reza Karkhaneh1
1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Purpose:
To present a rare manifestation of macular telangiectasia type 2 (MacTel type 2) followed up for over six years.
Methods:
A 61-year-old woman with one year history of blurred vision of her left eye was referred.
Results:
Whereas the funduscopy, spectral-domain optical coherence tomography (SD-OCT), fluorescein angiography (FA), and fundus autofluorescence (FAF) were normal in the right eye, they revealed noticeable findings typical of MacTel type 2 in the left eye. After over six years follow-up, OCT-angiography (OCTA) showed no remarkable difference between the two eyes, and en face OCT showed subtle abnormal change in the right eye as well as typical pathological changes in the left eye.
Conclusion:
MacTel type 2 can present unilaterally and remain so for a long time. The role of multimodal imaging in diagnosis and follow-up is of utmost importance.
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