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Related Experiment Video

Updated: Jan 31, 2026

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

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Published on: May 19, 2023

Short-Term Outcomes Predict Long-Term Satisfaction in Patients Undergoing Laparoscopic Magnetic Sphincter

Michael Antiporda¹, Chloe Jackson¹, C Daniel Smith²

¹1 Department of Surgery, Mayo Clinic in Florida , Jacksonville, Florida.

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A

|December 18, 2018

Summary

Laparoscopic magnetic sphincter augmentation (MSA) effectively treats refractory gastroesophageal reflux disease (GERD). This study shows durable symptom improvement and low dysphagia rates in patients undergoing MSA.

Keywords:

GERD laparoscopy magnetic sphincter augmentation outcomes

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Area of Science:

Gastroenterology
Minimally Invasive Surgery

Background:

Gastroesophageal reflux disease (GERD) significantly impacts quality of life.
Medical management is often insufficient for severe GERD.
Laparoscopic magnetic sphincter augmentation (MSA) is an option for refractory GERD.

Purpose of the Study:

To evaluate the outcomes of laparoscopic magnetic sphincter augmentation (MSA) for GERD.
To assess symptom improvement and quality of life changes post-MSA.
To analyze complication rates and long-term durability of MSA.

Main Methods:

Retrospective review of 98 patients undergoing laparoscopic MSA for GERD (2012-2016).
Assessment of symptoms using the GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire.
Objective testing included pH monitoring, manometry, endoscopy, and upper GI series; median follow-up was 46 months.

Main Results:

Significant reduction in GERD-HRQL scores from 25 preoperatively to 8 (short-term) and 5 (long-term) (P < .05).
Esophagitis present in 18%, hiatal hernia in 59%; 16% required full hiatal dissection.
Low complication rate; 5 patients (5%) required reoperation, including one device erosion. No intraoperative complications.

Conclusions:

Laparoscopic MSA demonstrates excellent efficacy for GERD treatment.
Symptom improvement is significant and durable long-term.
The procedure is associated with a low rate of new-onset dysphagia.